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chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase

Summary

Gene Symbol

ALG1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852407

KEGG Gene ID

sce:YBR110W

PubChem

852407

Alliance of Genome Resources

SGD:S000000314

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P16661	Asparagine-linked glycosylation protein 1 Beta-1,4-mannosyltransferase GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase GDP-mannose-dolichol diphosphochitobiose mannosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
oligosaccharide-lipid intermediate biosynthetic process
protein glycosylation	IBA IEA
protein N-linked glycosylation	IMP	6369318
dolichol-linked oligosaccharide biosynthetic process	IMP	7037780

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA
endoplasmic reticulum membrane	IEA
cytoplasmic side of endoplasmic reticulum membrane
endoplasmic reticulum	IBA IEA IPI	15044395

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of endoplasmic reticulum membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
chitobiosyldiphosphodolichol beta-mannosyltransferase activity	IEA
beta-1,4-mannosyltransferase activity	IDA	6368538
mannosyltransferase activity	IBA IEA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity

beta-1,4-mannosyltransferase activity

chitobiosyldiphosphodolichol beta-mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mannosyltransferase

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mannosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like

KEGG BRITE Database

Orthology

K03842

Name

beta-1,4-mannosyltransferase [EC:2.4.1.142]

References

10704531

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05972	2.4.1.142	G05026ZL	G65996GC

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
endoplasmic reticulum	PMID:15044395

Rhea

RHEA:13865

GDP-α-D-mannose

H⁺ + GDP

Enzyme

2.4.1.142

PMID

6215245

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050570	congenital disorder of glycosylation type I	Alliance of Genome Resources
DOID:0080563	congenital disorder of glycosylation Ik	Alliance of Genome Resources
DOID:5212	congenital disorder of glycosylation	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007132
Gene Name: chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase

Ortholog

Displaying entries **1 - 10** of 32 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	42146		FB:FBgn0038552
Homo sapiens	56052		HGNC:18294
Caenorhabditis elegans	175920		WB:WBGene00020820
Homo sapiens	200810		HGNC:33721
Mus musculus	208211		MGI:2384774
Danio rerio	334161		ZFIN:ZDB-GENE-030131-6093
Rattus norvegicus	360475		RGD:1310700
Xenopus tropicalis	594994		Xenbase:XB-GENE-1006362
Homo sapiens	644974		HGNC:37258
Kluyveromyces lactis	2896930	28985_0:0003ce

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements