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dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

Summary

Gene Symbol

STT3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852862

KEGG Gene ID

sce:YGL022W

PubChem

852862

Alliance of Genome Resources

SGD:S000002990

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Magnesium
Manganese
Metal-binding
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P39007	Staurosporine and temperature sensitivity protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IPI	9405463
protein N-linked glycosylation via asparagine	IBA
post-translational protein modification	IBA
protein glycosylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

post-translational protein modification

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

post-translational protein modification

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

post-translational protein modification

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

post-translational protein modification

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

post-translational protein modification

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	HDA IEA	26928762
endoplasmic reticulum membrane	IEA
oligosaccharyltransferase complex	IDA IPI	10358084 9405463
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

oligosaccharyltransferase complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
oligosaccharyl transferase activity	IEA
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IBA IC IEA	9405463
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

oligosaccharyl transferase activity

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07151

Name

dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]

References

12887896

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05976	2.4.99.18	G72079JG	G57930PW

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
oligosaccharyltransferase complex	PMID:10358084 PMID:9405463
endoplasmic reticulum	PMID:26928762

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080572	congenital disorder of glycosylation Iw	Alliance of Genome Resources
DOID:0080573	congenital disorder of glycosylation Ix	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007278
Gene Name: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

Ortholog

Displaying entries **1 - 10** of 11 in total

1

2

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	175886	WB:WBGene00020437
Drosophila melanogaster	33082	FB:FBgn0031149
Drosophila melanogaster	43005	FB:FBgn0011336
Danio rerio	266797	ZFIN:ZDB-GENE-021015-3
Danio rerio	323918	ZFIN:ZDB-GENE-030131-2638
Xenopus tropicalis	407861	Xenbase:XB-GENE-973638
Homo sapiens	3703	HGNC:6172
Homo sapiens	201595	HGNC:30611
Mus musculus	16430	MGI:105124
Mus musculus	68292	MGI:1915542

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Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements