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thiamine thiazole synthase

Summary

Gene Symbol

THI4

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853047

PubChem

853047

Alliance of Genome Resources

SGD:S000003376

Annotation

Keyword

3D-structure
Cytoplasm
Direct protein sequencing
Iron
Metal-binding
NAD
Nucleus
Reference proteome
Thiamine biosynthesis
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
P32318	Thiazole biosynthetic enzyme

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
thiamine biosynthetic process	IEA IMP	7941734
thiazole biosynthetic process	IDA IEA	22031445
mitochondrial genome maintenance	IMP	9367751

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial genome maintenance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IEA
cytosol	IDA IEA	15544818 16850348
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ferrous iron binding	IDA	22031445
transferase activity	IEA
iron ion binding	IEA
pentosyltransferase activity	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity [inference]

pentosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

iron ion binding

ferrous iron binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytosol	PMID:15544818 PMID:16850348

Rhea

RHEA:55708

glycine + NAD⁺

ADP-5-ethyl-4-methylthiazole-2-carboxylate + H₂O + H⁺ + nicotinamide

Enzyme

2.4.2.60

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements