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cystatin F

Summary

Gene Symbol

CST7

Organism

Homo sapiens (human)

External Links

NCBI Gene

8530

PubChem

8530

Alliance of Genome Resources

HGNC:2479

JoGo

CST7

TogoVar

CST7

Annotation

Keyword

3D-structure
Cytoplasm
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal
Thiol protease inhibitor

Proteins

Displaying 1 entry
UniProt	Protein Name
O76096	Cystatin-7 Cystatin-like metastasis-associated protein Leukocystatin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
regulation of antigen processing and presentation	IDA	22365146
immune response	TAS	18256700
negative regulation of peptidase activity
positive regulation of myelination	IBA
negative regulation of microglial cell activation	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of antigen processing and presentation

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of microglial cell activation [inference]

negative regulation of microglial cell activation

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of myelination

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of neuroinflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of microglial cell activation [inference]

negative regulation of microglial cell activation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of neuroinflammatory response [inference]

negative regulation of neuroinflammatory response [inference]

negative regulation of microglial cell activation

regulation of microglial cell activation [inference]

negative regulation of microglial cell activation

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of cellular process [inference]

regulation of myelination [inference]

positive regulation of myelination

positive regulation of cellular process [inference]

positive regulation of myelination

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of microglial cell activation [inference]

negative regulation of microglial cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of microglial cell activation [inference]

negative regulation of microglial cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation [inference]

negative regulation of microglial cell activation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

Displaying entries **6 - 10** of 12 in total

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GO Term	Evidence Code	PMID
late endosome	IBA
multivesicular body	IDA	22365146
endoplasmic reticulum	IDA	15212960 18256700
endoplasmic reticulum	IBA
Golgi apparatus	IDA	18256700 22365146

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

late endosome

multivesicular body

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

late endosome

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

late endosome

multivesicular body

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protease binding	IPI	15752368 22365146
endopeptidase inhibitor activity	TAS	9632704
cysteine-type endopeptidase inhibitor activity	IDA	15752368
cysteine-type endopeptidase inhibitor activity	IBA
protein binding	IPI	18256700