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ATP binding cassette subfamily C member 11

Summary

Gene Symbol

ABCC11

Organism

Homo sapiens (human)

External Links

NCBI Gene

85320

PubChem

85320

Alliance of Genome Resources

HGNC:14639

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cytoplasmic vesicle
Glycoprotein
Lipid transport
Reference proteome
Repeat
Translocase
Transmembrane helix
Vacuole

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96J66	Multidrug resistance-associated protein 8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
organic anion transport	IDA	15537867 16359813
organic anion transport	IBA
bile acid and bile salt transport	IDA	15537867
purine nucleotide transport	IDA	12764137 15537867
xenobiotic transport	IDA	15537867

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

xenobiotic transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

organic anion transport

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

icosanoid transport [inference]

leukotriene transport

organophosphate ester transport [inference]

nucleotide transport [inference]

purine nucleotide transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

icosanoid transport [inference]

leukotriene transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
vacuolar membrane	IEA
plasma membrane	TAS
plasma membrane	IDA	16359813
plasma membrane	IBA
apical plasma membrane	IDA	16359813

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
organic anion transmembrane transporter activity	IDA	15537867
organic anion transmembrane transporter activity	IBA
ABC-type xenobiotic transporter activity	IDA	15537867
purine nucleotide transmembrane transporter activity	IDA	12764137 15537867

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

organic anion transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

ATPase-coupled inorganic anion transmembrane transporter activity

organophosphate ester transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled inorganic anion transmembrane transporter activity

ABC-type transporter activity [inference]

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

sulfur compound transmembrane transporter activity [inference]

ABC-type glutathione S-conjugate transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled inorganic anion transmembrane transporter activity

ABC-type transporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

multidrug resistance-associated

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 42 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	10057	WB:WBGene00003411
Caenorhabditis elegans	27416	WB:WBGene00003411
Danio rerio	85320	ZFIN:ZDB-GENE-050517-25
Danio rerio	94160	ZFIN:ZDB-GENE-050517-25
Caenorhabditis elegans	116721	WB:WBGene00003411
Danio rerio	181587	ZFIN:ZDB-GENE-050517-25
Danio rerio	244562	ZFIN:ZDB-GENE-050517-25
Danio rerio	291923	ZFIN:ZDB-GENE-050517-25
Pan troglodytes	473275		PANTR12308
Macaca mulatta	716552		MACMU27249