GlyCosmos Portal

Submissions

carbohydrate sulfotransferase 1

Summary

Gene Symbol

CHST1

Aliases

C6ST
KSGal6ST
Keratan sulfotransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

8534

GGDB ID

gg027

HGNC

1969

mRNA

NM_003654

map

11p11.2-p11.1

Protein

NP_003645

OMIM

603797

KEGG Gene ID

hsa:8534

PubChem

8534

Alliance of Genome Resources

HGNC:1969

Annotation

Keyword

Carbohydrate metabolism
Glycoprotein
Golgi apparatus
Inflammatory response
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O43916	Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1 Keratan sulfate Gal-6 sulfotransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
polysaccharide metabolic process	TAS	9405439
galactose metabolic process	IDA	10330415
N-acetylglucosamine metabolic process	IBA
sulfur compound metabolic process	IDA	10330415
inflammatory response	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

keratan sulfate metabolic process

keratan sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

keratan sulfate biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

cellular metabolic process [inference]

sulfur compound metabolic process

keratan sulfate metabolic process

keratan sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

keratan sulfate biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

keratan sulfate biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

keratan sulfate metabolic process

keratan sulfate biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

keratan sulfate metabolic process

keratan sulfate biosynthetic process

amino sugar metabolic process [inference]

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

keratan sulfate metabolic process

keratan sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process

keratan sulfate metabolic process

keratan sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

keratan sulfate biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

keratan sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

keratan sulfate biosynthetic process

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
trans-Golgi network
membrane	NAS	9405439

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
N-acetylglucosamine 6-O-sulfotransferase activity	IBA
protein binding	IPI	32296183
sulfotransferase activity	IDA	10330415
keratan sulfotransferase activity	TAS
keratan sulfotransferase activity	IDA	17690104 9405439

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sulfotransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 4** entries
Gene Ontology
N-acetylglucosamine 6-O-sulfotransferase activity
N-acetylglucosamine metabolic process
sulfotransferase activity
transferase activity

Displaying **all 2** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Sulfotransferase domain

GlycoGene Database (GGDB)

GGDB ID

gg027

Gene Symbol

CHST1

Reactions

Displaying **all 2** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Reference
PAPS	G00054MO		10642612
PAPS	G00055MO		10642612

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	XP_230293	XM_230293
Mus musculus	NP_076339	NM_023850

KEGG BRITE Database

Orthology

K01022

Name

keratan sulfate 6-sulfotransferase 1 [EC:2.8.2.21]

References

9405439

Ortholog

Displaying entries **1 - 10** of **121** in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	4166	FB:FBgn0051637
Xenopus tropicalis	8534	Xenbase:XB-GENE-1001308
Drosophila melanogaster	9435	FB:FBgn0051637
Drosophila melanogaster	9469	FB:FBgn0031826
Drosophila melanogaster	10164	FB:FBgn0051637
Drosophila melanogaster	23563	FB:FBgn0031826
Drosophila melanogaster	26887	FB:FBgn0051637
Danio rerio	33913	ZFIN:ZDB-GENE-040801-21
Xenopus tropicalis	33914	Xenbase:XB-GENE-1001308
Drosophila melanogaster	53374	FB:FBgn0051637

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements