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FG-nucleoporin NSP1

Summary

Gene Symbol

NSP1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853409

PubChem

853409

Alliance of Genome Resources

SGD:S000003577

Annotation

Keyword

3D-structure
Coiled coil
Membrane
Nuclear pore complex
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
P14907	Nuclear pore protein NSP1 Nucleoskeletal-like protein p110

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
NLS-bearing protein import into nucleus	IGI	15039779
tRNA export from nucleus	IMP	8524308
protein transport	IEA
mRNA transport	IEA
ribosomal large subunit export from nucleus	IMP	11071906 11739405 9971735

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

localization [inference]

protein-containing complex localization [inference]

ribosomal subunit export from nucleus [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of organelle localization [inference]

ribosomal subunit export from nucleus [inference]

organelle localization [inference]

ribosome localization [inference]

ribosomal subunit export from nucleus [inference]

establishment of organelle localization [inference]

ribosomal subunit export from nucleus [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

RNA export from nucleus

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nuclear membrane	IEA
membrane	IEA
nuclear pore nuclear basket	IDA	9813081
nuclear pore central transport channel	IBA IDA	18046406 24574455 9813081
nuclear pore	IDA IEA	10684247 2112428

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
structural constituent of nuclear pore	IBA IDA IEA IPI	12169684 17418788 19098896 19680227
phospholipid binding	IBA IDA	17897934

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

lipid binding [inference]

phospholipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nucleoporin

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
RNA export from nucleus
phospholipid binding
protein import into nucleus

Displaying **all 2** entries
InterPro
Nucleoporin NSP1/NUP62
Nucleoporin, NSP1-like, C-terminal

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
nuclear periphery	PMID:22842922
nuclear pore central transport channel	PMID:18046406 PMID:24574455 PMID:9813081
nuclear pore nuclear basket	PMID:9813081
nuclear pore	PMID:10684247 PMID:2112428

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:12236	primary biliary cholangitis	Alliance of Genome Resources
DOID:4751	striatonigral degeneration	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	Alliance of Genome Resources
Mus musculus	18226	MGI:1351500
Homo sapiens	23636	HGNC:8066
Drosophila melanogaster	36830	FB:FBgn0034118
Homo sapiens	54830	HGNC:25960
Rattus norvegicus	65274	RGD:619938
Caenorhabditis elegans	171954	WB:WBGene00003797
Mus musculus	279706	MGI:2685565
Rattus norvegicus	300923	RGD:1564353
Xenopus tropicalis	394934	Xenbase:XB-GENE-6257978
Danio rerio	563392	ZFIN:ZDB-GENE-030131-8491