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GTPase-activating protein BUD2

Summary

Gene Symbol

BUD2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853770

PubChem

853770

Alliance of Genome Resources

SGD:S000001575

Annotation

Keyword

Acetylation
GTPase activation
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P33314	Bud site selection protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mitotic spindle orientation checkpoint signaling	IMP	22558355
invasive growth in response to glucose limitation	IMP	23783029
establishment or maintenance of cell polarity	IMP	23783029
axial cellular bud site selection	IMP	2065354 22558355
bipolar cellular bud site selection	IMP	2065354

GO Hierarchy

biological process

reproduction [inference]

asexual reproduction [inference]

cell budding [inference]

reproduction of a single-celled organism [inference]

cell budding [inference]

cellular process [inference]

establishment or maintenance of cell polarity

establishment of cell polarity [inference]

cellular bud site selection [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

cell cycle process [inference]

mitotic cell cycle process [inference]

cellular bud site selection [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

cell division [inference]

cell budding [inference]

growth [inference]

filamentous growth

filamentous growth of a population of unicellular organisms [inference]

growth of unicellular organism as a thread of attached cells [inference]

invasive filamentous growth

invasive growth in response to glucose limitation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
incipient cellular bud site	IDA	10444589
cellular bud neck	HDA IDA	10444589 14562095
prospore membrane	HDA	24390141
cytoplasm	HDA	14562095

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

incipient cellular bud site

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

prospore membrane

site of polarized growth [inference]

cellular bud neck

Displaying 1 entry
GO Term	Evidence Code	PMID
GTPase activator activity	IDA IEA	8371782

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

GTPase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Ras GTPase-activating domain
Ras GTPase-activating protein, conserved site
RasGAP protein, C-terminal
Rho GTPase activation protein

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cellular bud neck	PMID:10444589 PMID:14562095
incipient cellular bud site	PMID:10444589
prospore membrane	PMID:24390141
cytoplasm	PMID:14562095

Disease

Disease Ontology

Displaying entries **1 - 10** of 21 in total

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DO ID	Disease Name	Source
DOID:0050830	peripheral artery disease	Alliance of Genome Resources
DOID:0060037	developmental disorder of mental health	Alliance of Genome Resources
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0070035	autosomal dominant intellectual developmental disorder 5	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:1289	neurodegenerative disease	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 43 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Mus musculus	240057		MGI:3039785
Rattus norvegicus	304893		RGD:1307566
Rattus norvegicus	314596		RGD:1309019
Mus musculus	320484		MGI:2444128
Danio rerio	558237		ZFIN:ZDB-GENE-030131-2449
Danio rerio	793730		ZFIN:ZDB-GENE-070912-180
Danio rerio	798492		ZFIN:ZDB-GENE-101130-3
Kluyveromyces lactis	2897033	28985_0:000394
Eremothecium gossypii ATCC 10895	4619059	284811_0:0001b7
Vanderwaltozyma polyspora DSM 70294	5542505	436907_0:0000d9