GlyCosmos Portal

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GO Term	Evidence Code	PMID
ATP-dependent protein folding chaperone	IEA
hydrolase activity	IEA
ATP hydrolysis activity	IEA
ATP binding	IDA IEA IMP	19759005
adenyl-nucleotide exchange factor activity	IBA IDA	14704430

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

unfolded protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

protein folding chaperone [inference]

ATP-dependent protein folding chaperone

molecular function regulator activity [inference]

ATPase regulator activity [inference]

adenyl-nucleotide exchange factor activity

ATP-dependent activity [inference]

ATP-dependent protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

heat shock protein

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
ATP-dependent protein folding chaperone
endoplasmic reticulum unfolded protein response
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
nucleotide binding

Displaying **all 4** entries
InterPro
ATPase, nucleotide binding domain
Heat shock protein 70 family
Heat shock protein 70kD, C-terminal domain superfamily
Heat shock protein 70kD, peptide-binding domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
endoplasmic reticulum	PMID:26928762
endoplasmic reticulum lumen	PMID:8654361 PMID:8887673

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111974	immunodeficiency 59	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	10525		HGNC:16931
Mus musculus	12282		MGI:108030
Drosophila melanogaster	31215		FB:FBgn0023529
Caenorhabditis elegans	181422		WB:WBGene00011771
Rattus norvegicus	192235		RGD:621146
Danio rerio	327133		ZFIN:ZDB-GENE-030131-5344
Xenopus tropicalis	779444		Xenbase:XB-GENE-921821
Kluyveromyces lactis	2894852	28985_0:001395
Eremothecium gossypii ATCC 10895	4620385	284811_0:0006b8
Vanderwaltozyma polyspora DSM 70294	5544003	436907_0:000638