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putative ATP-binding cassette multidrug transporter VMR1

Summary

Gene Symbol

VMR1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856350

PubChem

856350

Alliance of Genome Resources

SGD:S000001027

Annotation

Keyword

ATP-binding
Glycoprotein
Reference proteome
Repeat
Transmembrane helix
Transport
Vacuole

Proteins

Displaying 1 entry
UniProt	Protein Name
P38735	Vacuolar multidrug resistance protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
response to metal ion	IMP	20846144
transmembrane transport	IBA IEA
xenobiotic detoxification by transmembrane export across the plasma membrane	IGI IMP	20846144

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

response to stimulus [inference]

response to chemical [inference]

response to inorganic substance [inference]

response to metal ion

localization [inference]

establishment of localization [inference]

transport [inference]

xenobiotic transport [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IEA
fungal-type vacuole membrane	IBA IDA	20846144 23658021
vacuole	IEA
mitochondrion	HDA	14576278 16823961
vacuolar membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane

lytic vacuole membrane [inference]

fungal-type vacuole membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ABC-type transporter activity	IEA
ATP hydrolysis activity	IEA
ATPase-coupled transmembrane transporter activity	IBA
ABC-type xenobiotic transporter activity	ISA	9020838
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
mitochondrion	PMID:14576278 PMID:16823961
fungal-type vacuole membrane	PMID:20846144 PMID:23658021

Ortholog

Displaying entries **1 - 10** of 14 in total

1

2

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	34140		FB:FBgn0032018
Drosophila melanogaster	34350		FB:FBgn0028675
Homo sapiens	89845		HGNC:52
Mus musculus	224814		MGI:2386976
Rattus norvegicus	316231		RGD:1306696
Danio rerio	553281		ZFIN:ZDB-GENE-050517-22
Danio rerio	556709		ZFIN:ZDB-GENE-050517-24
Saccharomyces eubayanus	28933950	1080349_0:000936
Saccharomyces paradoxus	54630943	27291_0:000929
Saccharomyces mikatae IFO 1815	80918556	226126_0:0009cd

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Acknowledgements