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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
nucleotide diphosphatase/phosphodiesterase NPP2
Summary
- Gene Symbol
-
- NPP2
- Organism
- Saccharomyces cerevisiae S288C
Annotation
- Keyword
-
- Glycoprotein
- Hydrolase
- Multifunctional enzyme
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P39997 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphate-containing compound metabolic process | ||
| nucleoside triphosphate metabolic process | ||
| organophosphate metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| endoplasmic reticulum |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ribonucleoside triphosphate phosphatase activity | ||
| zinc ion binding | ||
| hydrolase activity | ||
| phosphodiesterase I activity | ||
| nucleoside triphosphate diphosphatase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| nucleoside triphosphate diphosphatase activity |
| InterPro |
|---|
| Alkaline-phosphatase-like, core domain superfamily |
| Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050644 | arterial calcification of infancy | |
| DOID:0060887 | ossification of the posterior longitudinal ligament of spine | |
| DOID:0080333 | aortic valve disease 1 | |
| DOID:10754 | otitis media | |
| DOID:1123 | spondyloarthropathy | |
| DOID:1214 | tympanosclerosis | |
| DOID:1287 | cardiovascular system disease | |
| DOID:13207 | proliferative diabetic retinopathy | |
| DOID:2738 | pseudoxanthoma elasticum | |
| DOID:3068 | glioblastoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5167 | HGNC:3356 | |||
| 5168 | HGNC:3357 | |||
| 5169 | HGNC:3358 | |||
| 18605 | MGI:97370 | |||
| 18606 | MGI:1321390 | |||
| 22875 | HGNC:3359 | |||
| 54410 | RGD:708511 | |||
| 59084 | HGNC:13717 | |||
| 83965 | MGI:1933830 | |||
| 84050 | RGD:69298 |
