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Guidelines

MIRAGE

1,4-alpha-glucan branching enzyme

Summary

Gene Symbol

GLC3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856705

PubChem

856705

Alliance of Genome Resources

SGD:S000000737

Annotation

Keyword

Glycogen biosynthesis
Glycosyltransferase
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P32775	Glycogen-branching enzyme

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
glycogen biosynthetic process	IMP	1729600
glycogen biosynthetic process	IBA
glycogen biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen biosynthetic process

glucan biosynthetic process [inference]

glycogen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen biosynthetic process

glucan biosynthetic process [inference]

glycogen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen biosynthetic process

glucan biosynthetic process [inference]

glycogen biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

glycogen biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
cytoplasm	IEA
cytoplasm	HDA	14562095 22842922

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying entries **1 - 5** of 6 in total

1

2

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Last »
GO Term	Evidence Code	PMID
1,4-alpha-glucan branching enzyme activity	IMP	1729600
1,4-alpha-glucan branching enzyme activity	IBA
1,4-alpha-glucan branching enzyme activity	IEA
hydrolase activity, hydrolyzing O-glycosyl compounds	IEA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

1,4-alpha-glucan branching enzyme activity

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds

binding [inference]

ion binding [inference]

cation binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

1,4-alpha-glucan-branching enzyme 1

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
1,4-alpha-glucan branching enzyme activity
catalytic activity
cation binding
glycogen biosynthetic process
starch metabolic process
transferase activity

Displaying **all 8** entries
InterPro
1,4-alpha-glucan-branching enzyme
Alpha-amylase/branching enzyme, C-terminal all beta
Glycoside hydrolase superfamily
Glycoside hydrolase, family 13, N-terminal
Glycosyl hydrolase, all-beta
Glycosyl hydrolase, family 13, catalytic domain
Immunoglobulin E-set
Immunoglobulin-like fold

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytoplasm	PMID:14562095 PMID:22842922

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2750	glycogen storage disease IV	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2632	Xenbase:XB-GENE-980510
Xenopus tropicalis	74185	Xenbase:XB-GENE-980510
Xenopus tropicalis	856705	Xenbase:XB-GENE-980510

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025