Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
cyclin dependent kinase 13
Summary
- Gene Symbol
-
- CDK13
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Disease variant
- Host-virus interaction
- Intellectual disability
- Isopeptide bond
- Nucleus
- Phosphoprotein
- RNA editing
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- mRNA splicing
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| alternative mRNA splicing, via spliceosome | ||
| alternative mRNA splicing, via spliceosome | ||
| regulation of signal transduction | ||
| hemopoiesis | ||
| positive regulation of transcription elongation by RNA polymerase II |
GO Hierarchy
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cyclin K-CDK13 complex | ||
| extracellular region | ||
| extracellular space | ||
| nucleus | ||
| nucleoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA binding | ||
| protein kinase activity | ||
| cyclin-dependent protein serine/threonine kinase activity | ||
| protein binding | ||
| ATP binding |
GO Hierarchy
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
kinase activity [inference]
protein kinase activity
protein serine/threonine kinase activity [inference]
RNA polymerase II CTD heptapeptide repeat kinase activity
phosphotransferase activity, alcohol group as acceptor [inference]
protein kinase activity
protein serine/threonine kinase activity [inference]
RNA polymerase II CTD heptapeptide repeat kinase activity
catalytic activity, acting on a protein [inference]
protein kinase activity
protein serine/threonine kinase activity [inference]
RNA polymerase II CTD heptapeptide repeat kinase activity
RNA polymerase II CTD heptapeptide repeat modifying activity [inference]
RNA polymerase II CTD heptapeptide repeat kinase activity
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- kinase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| RNA polymerase II CTD heptapeptide repeat kinase activity |
| kinase activity |
| nucleotide binding |
| phosphorylation |
| transferase activity |
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase, ATP binding site |
| Protein kinase-like domain superfamily |
| Serine/threonine-protein kinase, active site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112247 | congenital heart defects, dysmorphic facial features, and intellectual developmental disorder | |
| DOID:10286 | prostate carcinoma | |
| DOID:1059 | intellectual disability | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 8621 | Xenbase:XB-GENE-6040279 | ||
| 51755 | SGD:S000001622 | ||
| 69131 | SGD:S000001622 | ||
| 69562 | Xenbase:XB-GENE-6040279 | ||
| 736969 | PANTR40109 | ||
| 103181579 | CALMI23023 | ||
| 103183858 | CALMI28358 | ||
| 104663119 | RHIRO06196 | ||
| 105497753 | MACNE40486 | ||
| 105597081 | CERAT10994 |
