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dynein axonemal heavy chain 17

Summary

Gene Symbol

DNAH17

Organism

Homo sapiens (human)

External Links

NCBI Gene

8632

PubChem

8632

Alliance of Genome Resources

HGNC:2946

JoGo

DNAH17

TogoVar

DNAH17

Annotation

Keyword

ATP-binding
Alternative splicing
Coiled coil
Cytoskeleton
Disease variant
Dynein
Flagellum
Microtubule
Motor protein
Proteomics identification
Reference proteome
Repeat
TPR repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UFH2	Axonemal beta dynein heavy chain 17 Axonemal dynein heavy chain-like protein 1 Ciliary dynein heavy chain 17 Ciliary dynein heavy chain-like protein 1 Dynein axonemal light chain 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
outer dynein arm assembly	IDA	31178125
cilium-dependent cell motility	NAS	9373155
cilium movement involved in cell motility	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
axonemal dynein complex	NAS	9373155
microtubule	IEA
axoneme	IDA	31178125
axoneme	IBA
dynein complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex

axonemal dynein complex

outer dynein arm

catalytic complex [inference]

dynein complex

axonemal dynein complex

outer dynein arm

cellular anatomical entity [inference]

axoneme

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

sperm flagellum

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
microtubule motor activity	NAS	9373155
ATP binding	IEA
minus-end-directed microtubule motor activity	IBA
dynein intermediate chain binding	IBA
dynein light intermediate chain binding	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dynein heavy chain

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity
nucleotide binding

Displaying entries **1 - 10** of 18 in total

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InterPro
Dynein heavy chain 3, AAA+ lid domain
Dynein heavy chain AAA lid domain superfamily
Dynein heavy chain AAA lid domain
Dynein heavy chain region D6 P-loop domain
Dynein heavy chain, AAA 5 extension domain
Dynein heavy chain, AAA module D4
Dynein heavy chain, AAA1 domain, small subdomain
Dynein heavy chain, ATP-binding dynein motor region
Dynein heavy chain, C-terminal domain, barrel region
Dynein heavy chain, C-terminal domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111926	spermatogenic failure 39	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements