GlyCosmos Portal

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
apical plasma membrane	IBA IMP ISS	15791618
recycling endosome membrane	ISS
plasma membrane	IDA IMP TAS	20010382 22262466 24643070 29507376 30431138
endosome	ISS
recycling endosome	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

recycling endosome membrane

plasma membrane region [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

intercellular canaliculus

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular canaliculus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
bile acid transmembrane transporter activity	IMP ISS	20010382 20398791 29507376
ABC-type xenobiotic transporter activity	IMP ISS	18245269
ABC-type bile acid transporter activity	IBA IDA IMP ISS TAS	15791618 15901796 18985798 32203132
canalicular bile acid transmembrane transporter activity	IBA IDA IMP ISS	22262466 24711118 32203132

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

carbohydrate transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity [inference]

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:0070222	progressive familial intrahepatic cholestasis 2	Alliance of Genome Resources
DOID:0070232	benign recurrent intrahepatic cholestasis 2	Alliance of Genome Resources
DOID:12351	alcoholic hepatitis	Alliance of Genome Resources
DOID:13580	cholestasis	Alliance of Genome Resources
DOID:1485	cystic fibrosis	Alliance of Genome Resources
DOID:1852	intrahepatic cholestasis	Alliance of Genome Resources
DOID:5082	liver cirrhosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 99 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	27413		MGI:1351619	MOUSE32013
Drosophila melanogaster	36582		FB:FBgn0010241
Rattus norvegicus	83569		RGD:619930	RATNO28108
Caenorhabditis elegans	172262		WB:WBGene00003996
Caenorhabditis elegans	178215		WB:WBGene00003995
Caenorhabditis elegans	180165		WB:WBGene00004003
Caenorhabditis elegans	181326		WB:WBGene00003997
Pan troglodytes	470717	9598_0:000c92		PANTR29050
Canis lupus familiaris	488390			CANLF13939
Bos taurus	531150			BOVIN24130

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Acknowledgements