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TNF receptor superfamily member 25

Summary

Gene Symbol

TNFRSF25

Organism

Homo sapiens (human)

External Links

NCBI Gene

8718

PubChem

8718

Alliance of Genome Resources

HGNC:11910

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Cell membrane
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q93038	Apo-3 Apoptosis-inducing receptor AIR Apoptosis-mediating receptor DR3 Apoptosis-mediating receptor TRAMP Death receptor 3 Lymphocyte-associated receptor of death Protein WSL Protein WSL-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
apoptotic process	NAS	9114039
signal transduction	TAS	8875942 8994832
cell surface receptor signaling pathway	TAS	9052839
tumor necrosis factor-mediated signaling pathway	IEA
regulation of apoptotic process	NAS	9114039

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

apoptotic signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

apoptotic signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
cytosol	NAS	9114039
plasma membrane	TAS
plasma membrane	IDA	11911831
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor activity	TAS	9052839
signaling receptor activity	NAS	9114039

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

death receptor activity [inference]

tumor necrosis factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tumor necrosis factor receptor superfamily member 25

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Death domain
Death-like domain superfamily
TNFR/NGFR cysteine-rich region
Tumour necrosis factor receptor 25

Ortholog

Displaying entries **1 - 10** of 36 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	7132	ZFIN:ZDB-GENE-141211-78
Danio rerio	8718	ZFIN:ZDB-GENE-141211-78
Danio rerio	21937	ZFIN:ZDB-GENE-141211-78
Danio rerio	25625	ZFIN:ZDB-GENE-141211-78
Mus musculus	85030		MOUSE40280
Rattus norvegicus	500592		RATNO33410
Pan troglodytes	749145		PANTR19807
Bos taurus	783432		BOVIN08385
Ornithorhynchus anatinus	100075718		ORNAN21568
Oryctolagus cuniculus	100351174		RABIT04284