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synaptosome associated protein 23

Summary

Gene Symbol

SNAP23

Organism

Homo sapiens (human)

External Links

NCBI Gene

8773

PubChem

8773

Alliance of Genome Resources

HGNC:11131

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell membrane
Coiled coil
Direct protein sequencing
Palmitate
Phosphoprotein
Protein transport
Reference proteome
Repeat
Synaptosome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K287
O00161	Vesicle-membrane fusion protein SNAP-23

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
histamine secretion by mast cell	IMP	18253931
exocytosis	IBA
post-Golgi vesicle-mediated transport	TAS	9727496
vesicle targeting	TAS	8663154
protein transport	IEA

GO Hierarchy

biological process

cellular process [inference]

vesicle targeting

vesicle-mediated transport [inference]

exocytosis

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion [inference]

vesicle fusion to plasma membrane [inference]

synaptic vesicle fusion to presynaptic active zone membrane

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

vesicle fusion to plasma membrane [inference]

synaptic vesicle fusion to presynaptic active zone membrane

cellular component assembly [inference]

protein-containing complex assembly [inference]

synaptic vesicle priming

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

synaptic vesicle priming

membrane organization [inference]

synaptic vesicle membrane organization [inference]

synaptic vesicle fusion to presynaptic active zone membrane

membrane fusion

organelle membrane fusion [inference]

vesicle fusion [inference]

vesicle fusion to plasma membrane [inference]

synaptic vesicle fusion to presynaptic active zone membrane

exocytic process [inference]

vesicle fusion to plasma membrane [inference]

synaptic vesicle fusion to presynaptic active zone membrane

export from cell [inference]

secretion by cell [inference]

exocytosis

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

vesicle-mediated transport [inference]

exocytosis

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport

secretion [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

secretion by cell [inference]

exocytosis

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

organic substance transport [inference]

protein transport

histamine transport [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

nitrogen compound transport [inference]

protein transport

histamine transport [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

export from cell [inference]

secretion by cell [inference]

exocytosis

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

histamine secretion by mast cell

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
nucleoplasm	IDA
cytoplasm	IDA	18457912
mitochondrion	IDA	26733245
plasma membrane	TAS
plasma membrane	IDA	18253931 18457912 26733245

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

SNARE complex

synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

bounding membrane of organelle [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-substrate junction [inference]

focal adhesion

cell projection [inference]

plasma membrane bounded cell projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

presynapse

Displaying **all 5** entries
GO Term	Evidence Code	PMID
SNAP receptor activity	IBA
protein binding	IPI	12773094 16189514 21900206 24373201 24705354 25416956 26359495 30833792 32296183 33961781 35271311
syntaxin-1 binding
syntaxin binding	IBA
syntaxin binding	IPI	16677249

GO Hierarchy

molecular function

binding [inference]

protein binding

SNARE binding [inference]

syntaxin binding

syntaxin-1 binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

SNAP receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome b561

Functional Category

C: Energy production and conversion
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	6616	SGD:S000003241
Xenopus tropicalis	8773	Xenbase:XB-GENE-942565
Saccharomyces cerevisiae S288C	20614	SGD:S000003241
Mus musculus	20619		MOUSE32166
Rattus norvegicus	64630		RATNO27891
Danio rerio	393159		DANRE12434
Pan troglodytes	453365		PANTR10095
Canis lupus familiaris	478268		CANLF12436
Bos taurus	522423		BOVIN01093
Macaca mulatta	708225		MACMU41614