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lipid-A-disaccharide synthase

Summary

Gene Symbol

lpxB

Organism

Pseudomonas aeruginosa PAO1

External Links

NCBI Gene: 880521
PubChem: 880521

Annotation

Keyword

Glycosyltransferase
Lipid A biosynthesis
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HXY8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lipopolysaccharide biosynthetic process	ISS	3531165
lipid A biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipooligosaccharide biosynthetic process [inference]

lipid A biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipooligosaccharide biosynthetic process [inference]

lipid A biosynthetic process

lipooligosaccharide metabolic process [inference]

lipid A metabolic process [inference]

lipid A biosynthetic process

lipooligosaccharide biosynthetic process [inference]

lipid A biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipooligosaccharide biosynthetic process [inference]

lipid A biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

lipid A biosynthetic process

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

lipid A biosynthetic process

lipid A metabolic process [inference]

lipid A biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
phospholipid binding
lipid-A-disaccharide synthase activity
glycosyltransferase activity	ISS	18838391

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

lipid-A-disaccharide synthase activity

hexosyltransferase activity [inference]

lipid-A-disaccharide synthase activity

binding [inference]

lipid binding [inference]

phospholipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Bacteria

Group Name

methyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
lipid A biosynthetic process
lipid metabolic process
lipid-A-disaccharide synthase activity
phospholipid binding
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 19

Rhea

RHEA:67828

a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-α-D-glucosamine + a lipid X

H⁺ + a lipid A disaccharide + UDP

Enzyme

2.4.1.182

PMID

RHEA:22668

2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

H⁺ + UDP + lipid A disaccharide (E. coli)

Enzyme

2.4.1.182

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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OrthoDB (Group)

International Collaboration

Acknowledgements