GlyCosmos Portal

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lactosylceramide alpha-2,3-sialyltransferase activity	IBA IDA	9822625
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	TAS
sialyltransferase activity	TAS	10092602

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000115525

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg052

Gene Symbol

ST3GAL5

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_112627	NM_031337
Mus musculus	NP_035505	NM_011375

KEGG BRITE Database

Orthology

K03370

Name

lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.3.9]

References

9875239

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05937	2.4.3.9	G84224TW	G91237TK

Rhea

RHEA:18417

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + a ganglioside GM3 (d18:1(4E)) + CMP

Enzyme

2.4.3.9

PMID

Disease

Disease Ontology

Displaying entries **31 - 40** of **105** in total

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DO ID	Disease Name	Source
DOID:0110781	hereditary spastic paraplegia 30	DisGeNET
DOID:0110782	hereditary spastic paraplegia 31	DisGeNET
DOID:0110783	hereditary spastic paraplegia 32	DisGeNET
DOID:0110785	hereditary spastic paraplegia 34	DisGeNET
DOID:0110786	hereditary spastic paraplegia 35	DisGeNET
DOID:0110787	hereditary spastic paraplegia 36	DisGeNET
DOID:0110788	hereditary spastic paraplegia 37	DisGeNET
DOID:0110789	hereditary spastic paraplegia 38	DisGeNET
DOID:0110790	hereditary spastic paraplegia 39	DisGeNET
DOID:0110791	hereditary spastic paraplegia 3A	DisGeNET

The Human Phenotype Ontology

Displaying entries **11 - 20** of 26 in total

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HPO ID	HPO Term
HP:0001336	Myoclonus
HP:0001344	Absent speech
HP:0001508	Failure to thrive
HP:0002013	Vomiting
HP:0002069	Bilateral tonic-clonic seizure
HP:0002133	Status epilepticus
HP:0002283	Global brain atrophy
HP:0002376	Developmental regression
HP:0002395	Lower limb hyperreflexia
HP:0003593	Infantile onset

Displaying 1 entry
Disease ID	Disease Name
OMIM:609056	GM3 synthase deficiency

PubChem Disease

GHR Health Conditions

GM3 synthase deficiency

MedGen Diseases

GM3 synthase deficiency

OMIM Phenotypes

SALT AND PEPPER DEVELOPMENTAL REGRESSION SYNDROME; SPDRS

KEGG Diseases

Amish infantile epilepsy syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000401
Gene Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Ortholog

Displaying entries **31 - 40** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Tursiops truncatus	101335126	TURTR10255
Balaenoptera musculus	118906137	BALMU04863
Loxodonta africana	100673997	LOXAF03801
Equus caballus	100067118	HORSE09497
Equus caballus	111771968	HORSE09497
Equus caballus	111771995	HORSE09497
Sus scrofa	100625751	PIGXX21673
Bos taurus	404164	BOVIN02558
Capra hircus	102190883	CAPHI01904
Ovis aries	101104977	SHEEP13755

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements