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H1.10 linker histone

Summary

Gene Symbol

H1-10

Organism

Homo sapiens (human)

External Links

NCBI Gene

8971

PubChem

8971

Alliance of Genome Resources

HGNC:4722

JoGo

H1-10

TogoVar

H1-10

Annotation

Keyword

3D-structure
Acetylation
Chromosome
Citrullination
DNA-binding
Direct protein sequencing
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q92522	Histone H1x

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleosome assembly	IEA
chromosome condensation	IBA
negative regulation of DNA recombination	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome condensation

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization [inference]

nucleosome assembly

protein-DNA complex assembly [inference]

nucleosome assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

negative regulation of DNA recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

negative regulation of DNA recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

negative regulation of DNA recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

negative regulation of DNA recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

negative regulation of DNA recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA recombination

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleosome	IEA
nucleus	IBA
nucleoplasm	IDA
chromosome	IDA
nucleolus	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

nucleosome

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
double-stranded DNA binding	IBA
RNA binding	HDA	22681889
structural constituent of chromatin	IEA
nucleosomal DNA binding	IBA
cadherin binding	HDA	25468996

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of chromatin

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cadherin binding

protein-containing complex binding [inference]

chromatin binding [inference]

chromatin DNA binding [inference]

nucleosomal DNA binding

nucleosome binding [inference]

nucleosomal DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

double-stranded DNA binding

chromatin DNA binding [inference]

nucleosomal DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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