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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
FYVE, RhoGEF and PH domain containing 3
Summary
- Gene Symbol
-
- FGD3
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of small GTPase mediated signal transduction | ||
| actin cytoskeleton organization | ||
| filopodium assembly | ||
| regulation of cell shape | ||
| regulation of GTPase activity |
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| ruffle | ||
| lamellipodium | ||
| cytoskeleton | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| small GTPase binding | ||
| metal ion binding | ||
| guanyl-nucleotide exchange factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Leucine rich repeat
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110192 | Charcot-Marie-Tooth disease type 4H | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:6683 | X-linked Aarskog syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 30938 | MGI:1353657 | MOUSE10761 | ||
| 177692 | WB:WBGene00001366 | |||
| 361223 | RGD:1311725 | RATNO12412 | ||
| 484213 | CANLF00520 | |||
| 512950 | BOVIN34944 | |||
| 706720 | MACMU12558 | |||
| 100056145 | HORSE22408 | |||
| 100173690 | 9601_0:00275a | PONAB35979 | ||
| 100221423 | TAEGU03658 | |||
| 100358225 | RABIT00383 |
