OTU deubiquitinase with linear linkage specificity

Summary
Gene Symbol
  • OTULIN
Organism
Homo sapiens (human)
NCBI Gene
90268
PubChem
90268
Alliance of Genome Resources
JoGo
OTULIN
TogoVar
OTULIN
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Angiogenesis
  • Cytoplasm
  • Disease variant
  • Innate immunity
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Thiol protease
  • Ubl conjugation
  • Ubl conjugation pathway
  • Wnt signaling pathway
Proteins
Displaying 1 entry
UniProt Protein Name
Q96BN8
  • Deubiquitinating enzyme otulin
  • OTU domain-containing deubiquitinase with linear linkage specificity
  • Ubiquitin thioesterase Gumby
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
inactive ubiquitin thioesterase
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying 1 entry
InterPro
FAM105
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0080163 otulipenia
DOID:612 primary immunodeficiency disease

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026