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polycystin 2 like 1, transient receptor potential cation channel

Summary

Gene Symbol

PKD2L1

Organism

Homo sapiens (human)

External Links

NCBI Gene

9033

PubChem

9033

Alliance of Genome Resources

HGNC:9011

JoGo

PKD2L1

TogoVar

PKD2L1

Annotation

Keyword

3D-structure
Alternative splicing
Calcium channel
Cell membrane
Cilium
Coiled coil
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Metal-binding
Palmitate
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q1L4F0	Polycystic kidney disease 2-like 1 protein Polycystin-2 homolog
Q9P0L9	Polycystic kidney disease 2-like 1 protein Polycystin-2 homolog Polycystin-L Polycystin-L1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of sour taste	ISS
monoatomic cation transport	ISS
smoothened signaling pathway	ISS
response to water	IEA
sodium ion transmembrane transport	IDA	10517637

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

response to water

detection of abiotic stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

response to chemical [inference]

response to acid chemical [inference]

response to water

response to organic substance [inference]

response to water

response to inorganic substance [inference]

response to water

response to oxygen-containing compound [inference]

response to water

response to salt [inference]

response to water

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

detection of abiotic stimulus [inference]

detection of mechanical stimulus

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste

detection of chemical stimulus involved in sensory perception of sour taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste

detection of chemical stimulus involved in sensory perception of sour taste

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	ISS
cytosol	IDA
plasma membrane	IDA	23212381 27754867
plasma membrane	IMP	17944866
cell surface	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

non-motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

non-motile cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
calcium-activated cation channel activity	IDA	10517637 11959145 24336289 25820328 27754867 29425510
monoatomic cation channel activity	IDA	17944866 30004384
calcium channel activity	IBA
sodium channel activity	IDA	10517637
sodium channel activity	IBA