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Guidelines

MIRAGE

C-C motif chemokine receptor like 2

Summary

Gene Symbol

CCRL2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9034

PubChem

9034

Alliance of Genome Resources

HGNC:1612

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2R8C0
O00421	Chemokine receptor CCR11 Chemokine receptor X Putative MCP-1 chemokine receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
chemotaxis	TAS	9473515
inflammatory response	ISS
inflammatory response	IBA
immune response	IBA
G protein-coupled receptor signaling pathway	TAS	9473515

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
plasma membrane	TAS
plasma membrane	IDA	20002784
external side of plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
chemokine receptor activity	TAS	9473515
protein binding	IPI	32296183
C-C chemokine receptor activity	IBA
C-C chemokine binding	IBA
chemokine receptor binding	IPI	14530373

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding

CCR chemokine receptor binding

cytokine receptor binding [inference]

chemokine receptor binding

CCR chemokine receptor binding

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity

C-C chemokine receptor activity

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity

C-C chemokine receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity

C-C chemokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

C-C chemokine receptor-like 2

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 9** entries
Gene Ontology
C-C chemokine binding
C-C chemokine receptor activity
calcium-mediated signaling
cell chemotaxis
chemokine receptor activity
chemokine-mediated signaling pathway
chemotaxis
immune response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
Chemokine receptor family
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 45 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	9034	RGD:1311811
Mus musculus	54199	RGD:1311811	MOUSE63669
Rattus norvegicus	316019		RATNO40621
Sus scrofa	414370		PIGXX03922
Pan troglodytes	460324		PANTR30965
Canis lupus familiaris	484788		CANLF07575
Bos taurus	515976		BOVIN17981
Macaca mulatta	713715		MACMU28263
Equus caballus	100054419		HORSE12242
Callithrix jacchus	100399503		CALJA11855

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Supported by JST NBDC Grant Number JPMJND2204

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025