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dual oxidase maturation factor 1

Summary

Gene Symbol

DUOXA1

Organism

Homo sapiens (human)

External Links

NCBI Gene

90527

PubChem

90527

Alliance of Genome Resources

HGNC:26507

Annotation

Keyword

3D-structure
Alternative splicing
Glycoprotein
Protein transport
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
B5M0B7
B5M0B8
B5M0C0
Q1HG43	Dual oxidase activator 1 Numb-interacting protein
A8K9Q6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein transport	IEA
regulation of thyroid hormone generation	IEA
hydrogen peroxide metabolic process	IEA
positive regulation of neuron differentiation	IEA
regulation of inflammatory response	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process

organic substance metabolic process [inference]

hydrogen peroxide metabolic process

cellular process [inference]

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

establishment of protein localization [inference]

protein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of thyroid hormone generation

regulation of hormone metabolic process [inference]

regulation of thyroid hormone generation

regulation of nitrogen compound metabolic process [inference]

regulation of thyroid hormone generation

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

regulation of hydrogen peroxide biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

regulation of thyroid hormone generation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide metabolic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of hydrogen peroxide biosynthetic process

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone metabolic process [inference]

regulation of thyroid hormone generation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA
endoplasmic reticulum membrane	IEA
cell leading edge	IGI	19339556
plasma membrane	IDA IEA	19339556
endoplasmic reticulum	IDA	19339556

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

cell leading edge

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	33420071
enzyme binding	IPI	19339556

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dual oxidase maturation factor

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Dual oxidase maturation factor

Ortholog

Displaying entries **1 - 10** of 57 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	34872		FB:FBgn0086711
Caenorhabditis elegans	182313		WB:WBGene00015519
Mus musculus	213696		MGI:2384861	MOUSE32888
Rattus norvegicus	311374		RGD:1306601	RATNO26891
Xenopus laevis	446687		Xenbase:XB-GENE-6255655
Pan troglodytes	453398	9598_0:003ec8		PANTR10215
Bos taurus	530151			BOVIN01423
Macaca mulatta	713058			MACMU40719
Xenopus tropicalis	780018		Xenbase:XB-GENE-990812
Monodelphis domestica	100012750			MONDO05254