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regucalcin

Summary

Gene Symbol

Aliases

RC
SMP30
gluconolactonase
senescence marker protein-30

Organism

Homo sapiens (human)

External Links

NCBI Gene

9104

HGNC

9989

KEGG Gene ID

hsa:9104

PubChem

9104

Alliance of Genome Resources

HGNC:9989

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cytoplasm
Hydrolase
Metal-binding
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
V9HWF8	Gluconolactonase Senescence marker protein 30
Q15493	Gluconolactonase Senescence marker protein 30

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
positive regulation of triglyceride biosynthetic process	IEA
negative regulation of flagellated sperm motility	IEA
negative regulation of apoptotic process	IEA
intracellular calcium ion homeostasis	ISS
positive regulation of fatty acid biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration [inference]

liver regeneration

animal organ development [inference]

kidney development

animal organ regeneration [inference]

liver regeneration

gland development [inference]

liver development [inference]

liver regeneration

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of nitric oxide metabolic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of DNA metabolic process [inference]

negative regulation of DNA metabolic process [inference]

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of triglyceride metabolic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of DNA metabolic process [inference]

negative regulation of DNA metabolic process [inference]

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of nitric oxide metabolic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of nitric oxide metabolic process [inference]

negative regulation of nitric oxide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of DNA metabolic process [inference]

negative regulation of DNA metabolic process [inference]

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of glucose metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

regulation of triglyceride metabolic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of DNA metabolic process [inference]

negative regulation of DNA metabolic process [inference]

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteolysis involved in protein catabolic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

regulation of cell motility [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

negative regulation of flagellated sperm motility

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of nitric oxide metabolic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

negative regulation of cellular process [inference]

negative regulation of cilium movement [inference]

negative regulation of flagellated sperm motility

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

negative regulation of developmental process [inference]

negative regulation of bone development

negative regulation of multicellular organismal process [inference]

negative regulation of bone development

negative regulation of reproductive process [inference]

negative regulation of flagellated sperm motility

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of bone development

regulation of multicellular organismal development [inference]

regulation of bone development [inference]

negative regulation of bone development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of DNA metabolic process [inference]

negative regulation of DNA metabolic process [inference]

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

negative regulation of DNA biosynthetic process

regulation of RNA biosynthetic process [inference]

negative regulation of RNA biosynthetic process

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

regulation of DNA catabolic process [inference]

negative regulation of DNA catabolic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of triglyceride metabolic process [inference]

regulation of triglyceride biosynthetic process [inference]

positive regulation of triglyceride biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement [inference]

negative regulation of cilium movement [inference]

negative regulation of flagellated sperm motility

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

negative regulation of flagellated sperm motility

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cilium movement [inference]

negative regulation of flagellated sperm motility

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of nitric oxide biosynthetic process

negative regulation of cellular catabolic process [inference]

negative regulation of DNA catabolic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

regulation of cell motility [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

negative regulation of flagellated sperm motility

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

negative regulation of cell motility [inference]

negative regulation of cilium-dependent cell motility [inference]

negative regulation of flagellated sperm motility

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of bone development

regulation of multicellular organismal development [inference]

regulation of bone development [inference]

negative regulation of bone development

regulation of reproductive process [inference]

regulation of flagellated sperm motility [inference]

negative regulation of flagellated sperm motility

negative regulation of reproductive process [inference]

negative regulation of flagellated sperm motility

regulation of molecular function [inference]

regulation of ATP-dependent activity [inference]

positive regulation of ATP-dependent activity

positive regulation of molecular function [inference]

positive regulation of ATP-dependent activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	ISS
cytoplasm	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
zinc ion binding	IDA	20329768
enzyme regulator activity	IEA
gluconolactonase activity	IBA IDA	20329768 23349732
calcium ion binding	IBA IDA ISS	20329768

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

gluconolactonase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

enzyme regulator activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000130988

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Rhea

RHEA:10440

H₂O + D-glucono-1,5-lactone

H⁺ + D-gluconate

Enzyme

3.1.1.17

PMID

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050387	nonpapillary renal cell carcinoma	DisGeNET
DOID:0050661	vitelliform macular dystrophy	DisGeNET
DOID:0060180	colitis	DisGeNET
DOID:0060189	ileitis	DisGeNET
DOID:0060190	ileocolitis	DisGeNET
DOID:0060262	gallbladder disease	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0080348	Alzheimer's disease 1	DisGeNET
DOID:0110035	Alzheimer's disease 2	DisGeNET
DOID:0110037	Alzheimer's disease 5	DisGeNET

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32165	FB:FBgn0030362
Drosophila melanogaster	41786	FB:FBgn0038257
Ciona intestinalis	100184729		CIOIN05193
Callorhinchus milii	103177110		CALMI12194
Latimeria chalumnae	102359731		LATCH03594
Danio rerio	403070	ZFIN:ZDB-GENE-040718-68	DANRE38911
Astyanax mexicanus	103028139		ASTMX05462
Ictalurus punctatus	100528098		ICTPU03503
Electrophorus electricus	113584068		ELEEL33040
Electrophorus electricus	113584069		ELEEL33039

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements