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Annotation

Keyword

Alternative splicing
Centromere
Chromosome
Cytoskeleton
Kinetochore
Mitosis
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96IK1	Biorientation defective protein 1 Protein FAM44B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein localization to chromosome, centromeric region	IMP	17938248 24157919
mitotic metaphase chromosome alignment	IMP	17938248
cell division	IEA
mitotic sister chromatid biorientation	IMP	17938248 24157919
negative regulation of phosphoprotein phosphatase activity

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

sister chromatid cohesion [inference]

mitotic sister chromatid cohesion [inference]

mitotic sister chromatid cohesion, centromeric

centromeric sister chromatid cohesion [inference]

mitotic sister chromatid cohesion, centromeric

attachment of spindle microtubules to kinetochore [inference]

sister chromatid biorientation [inference]

mitotic sister chromatid biorientation

attachment of mitotic spindle microtubules to kinetochore [inference]

mitotic sister chromatid biorientation

mitotic cell cycle process [inference]

mitotic metaphase chromosome alignment

attachment of mitotic spindle microtubules to kinetochore [inference]

mitotic sister chromatid biorientation

cell division

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

sister chromatid cohesion [inference]

mitotic sister chromatid cohesion [inference]

mitotic sister chromatid cohesion, centromeric

centromeric sister chromatid cohesion [inference]

mitotic sister chromatid cohesion, centromeric

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region

establishment of localization [inference]

establishment of localization in cell [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

organelle localization [inference]

chromosome localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of hydrolase activity [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
Set1C/COMPASS complex	IPI	23508102
nucleoplasm	TAS
spindle pole	IDA	17938248
outer kinetochore	IDA	17938248
centrosome	IDA	17938248 24157919

GO Hierarchy

cellular component

protein-containing complex [inference]

outer kinetochore

nuclear protein-containing complex [inference]

histone methyltransferase complex [inference]

Set1C/COMPASS complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex [inference]

Set1C/COMPASS complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

spindle microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183 32814053 33961781
protein phosphatase inhibitor activity	IDA	24157919
protein phosphatase 2A binding	IPI	24157919

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 2A binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Biorientation of chromosomes in cell division protein 1

Functional Category

K: Transcription
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell division

Displaying 1 entry
InterPro
Biorientation of chromosomes in cell division protein 1-like 1

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1059	intellectual disability	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	43352		FB:FBgn0039560
Mus musculus	69556		MGI:1916806	MOUSE03760
Rattus norvegicus	287173		RGD:1305622	RATNO02161
Xenopus laevis	446336		Xenbase:XB-GENE-6079024
Pan troglodytes	471746	9598_0:0017b4		PANTR36855
Xenopus tropicalis	493221		Xenbase:XB-GENE-5810100
Danio rerio	767743		ZFIN:ZDB-GENE-060810-163	DANRE22073
Monodelphis domestica	100031382			MONDO02207
Salmo salar	100195717			SALSA25951
Callithrix jacchus	100394653			CALJA27575

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Acknowledgements