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single-pass membrane protein with aspartate rich tail 1

Summary

Gene Symbol

SMDT1

Organism

Homo sapiens (human)

External Links

NCBI Gene

91689

PubChem

91689

Alliance of Genome Resources

HGNC:25055

JoGo

SMDT1

TogoVar

SMDT1

Annotation

Keyword

3D-structure
Calcium transport
Mitochondrion inner membrane
Proteomics identification
Reference proteome
Transit peptide
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9H4I9	Single-pass membrane protein with aspartate-rich tail 1, mitochondrial

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
mitochondrial calcium ion transmembrane transport	IMP	24231807 27099988 27642048
calcium import into the mitochondrion	NAS	24514027 31533452 31862210
calcium import into the mitochondrion	IDA	31080062 32315830 32494073 32762847 33296646
calcium import into the mitochondrion	IMP	27099988 27642048
calcium import into the mitochondrion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

mitochondrial transmembrane transport [inference]

calcium import into the mitochondrion

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

mitochondrial calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to calcium ion starvation

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

mitochondrial transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

mitochondrial transmembrane transport [inference]

calcium import into the mitochondrion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

mitochondrial transmembrane transport [inference]

calcium import into the mitochondrion

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

calcium import into the mitochondrion

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nucleoplasm	IDA
mitochondrion	IDA
mitochondrion	HTP	34800366
mitochondrial inner membrane	NAS	24514027 31533452 31862210
mitochondrial inner membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

inner mitochondrial membrane protein complex [inference]

uniplex complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex [inference]

uniplex complex

mitochondrial protein-containing complex [inference]

inner mitochondrial membrane protein complex [inference]

uniplex complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex [inference]

uniplex complex

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	27099988 27184846 27642048 28514442 32494073 33961781
protein-macromolecule adaptor activity	IDA	32494073 32762847
channel activator activity	IDA	31080062 32315830 33296646

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter activator activity [inference]

channel activator activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel activator activity

transporter activator activity [inference]

channel activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Essential MCU regulator mitochondrial

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
calcium import into the mitochondrion
calcium ion transport
mitochondrial calcium ion homeostasis
mitochondrial calcium ion transmembrane transport
monoatomic ion transport