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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
oncostatin M receptor
Summary
- Gene Symbol
-
- OSMR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Amyloidosis
- Disease variant
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q99650 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| oncostatin-M-mediated signaling pathway | ||
| response to cytokine | ||
| cytokine-mediated signaling pathway | ||
| positive regulation of acute inflammatory response |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| apical plasma membrane | ||
| receptor complex | ||
| plasma membrane | ||
| oncostatin-M receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine receptor activity | ||
| growth factor binding | ||
| oncostatin-M receptor activity | ||
| ciliary neurotrophic factor receptor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- oncostatin-M-specific receptor subunit beta
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ciliary neurotrophic factor receptor binding |
| cytokine-mediated signaling pathway |
| oncostatin-M receptor activity |
| positive regulation of cell population proliferation |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
| Leukemia inhibitory factor receptor, D2 domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080930 | primary localized cutaneous amyloidosis 1 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 18414 | MGI:1330819 | MOUSE15220 | ||
| 310132 | RGD:1302983 | RATNO24412 | ||
| 461908 | 9598_0:0016fc | PANTR35678 | ||
| 489223 | CANLF14997 | |||
| 541493 | ZFIN:ZDB-GENE-050327-16 | |||
| 565104 | ZFIN:ZDB-GENE-080107-2 | |||
| 693569 | MACMU39720 | |||
| 100066819 | HORSE20237 | |||
| 100076213 | ORNAN18588 | |||
| 100144562 | ZFIN:ZDB-GENE-060526-48 |
