replicase ORF1a polyprotein;replicase ORF1ab polyprotein
| UniProt | Protein Name |
|---|---|
| P19811 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| virus-mediated perturbation of host defense response |
|
|
| viral protein processing |
|
|
| suppression by virus of host type I interferon-mediated signaling pathway |
|
|
| suppression by virus of host ISG15-protein conjugation |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane |
|
|
| host cell membrane |
|
|
| host cell nucleus |
|
|
| host cell perinuclear region of cytoplasm |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA binding |
|
|
| RNA helicase activity |
|
|
| RNA-dependent RNA polymerase activity |
|
|
| cysteine-type endopeptidase activity |
|
|
| serine-type endopeptidase activity |
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: August 4, 2025