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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
activin A receptor type 2B
Summary
- Gene Symbol
-
- ACVR2B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Heterotaxy
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q13705 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| anterior/posterior pattern specification | ||
| lymphangiogenesis | ||
| organ growth | ||
| response to glucose | ||
| gastrulation with mouth forming second |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| activin receptor complex | ||
| protein-containing complex | ||
| receptor complex | ||
| plasma membrane | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| activin receptor activity, type II | ||
| transforming growth factor beta receptor activity | ||
| protein serine/threonine/tyrosine kinase activity | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein kinase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase-like domain superfamily |
| Ser/Thr protein kinase, TGFB receptor |
| Serine/threonine-protein kinase, active site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy | |
| DOID:0050787 | juvenile polyposis syndrome | |
| DOID:0060856 | right atrial isomerism | |
| DOID:10591 | pre-eclampsia | |
| DOID:14323 | Marfan syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11481 | MGI:87912 | MOUSE63996 | ||
| 25366 | RGD:2028 | RATNO41445 | ||
| 30457 | ZFIN:ZDB-GENE-980526-549 | DANRE25593 | ||
| 41772 | FB:FBgn0003169 | |||
| 175781 | WB:WBGene00000900 | |||
| 282131 | BOVIN17266 | |||
| 397859 | Xenbase:XB-GENE-17330678 | |||
| 399277 | Xenbase:XB-GENE-484252 | |||
| 448641 | Xenbase:XB-GENE-484248 | |||
| 448845 | PIGXX03774 |
