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zinc finger FYVE-type containing 9

Summary

Gene Symbol

ZFYVE9

Organism

Homo sapiens (human)

External Links

NCBI Gene

9372

PubChem

9372

Alliance of Genome Resources

HGNC:6775

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Endosome
Membrane
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
O95405	Mothers against decapentaplegic homolog-interacting protein Novel serine protease Receptor activation anchor Smad anchor for receptor activation

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endocytosis	NAS	12809483
transforming growth factor beta receptor signaling pathway	NAS	10615055
transforming growth factor beta receptor signaling pathway	IMP	9865696
transforming growth factor beta receptor signaling pathway	IBA
endosomal transport	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

vesicle-mediated transport [inference]

cellular localization [inference]

intracellular transport [inference]

endosomal transport

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

intracellular transport [inference]

endosomal transport

import into cell [inference]

endocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
early endosome	NAS	12809483
cytosol	IDA
early endosome membrane	TAS
early endosome membrane	IDA	11877415
early endosome membrane	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	10615055 12154125 12809483 15231748 17693260 18511908 22321011 24366813 25416956 25502805 31515488 33961781 9865696
1-phosphatidylinositol binding	IDA	11877415
zinc ion binding	IEA
protein domain specific binding	IPI	15231848
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

protein domain specific binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

1-phosphatidylinositol binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Zinc finger FYVE domain-containing protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
metal ion binding

Displaying **all 7** entries
InterPro
FYVE zinc finger
Smad anchor for receptor activation, Smad-binding domain superfamily
Smad anchor for receptor activation-like, C-terminal
Smad anchor for receptor activation-like, Smad-binding domain
Zinc finger, FYVE-related
Zinc finger, FYVE/PHD-type
Zinc finger, RING/FYVE/PHD-type