GlyCosmos Portal

Submissions

peptidoglycan glycosyltransferase (penicillin-binding proteins 1A and 1B)

Summary

Gene Symbol

ponA

Organism

Bacillus subtilis subsp. subtilis str. 168

External Links

NCBI Gene: 939044
KEGG Gene ID: bsu:BSU22320
PubChem: 939044

Annotation

Keyword

Antibiotic resistance
Carboxypeptidase
Cell membrane
Cell wall biogenesis/degradation
Direct protein sequencing
Glycosyltransferase
Multifunctional enzyme
Peptidoglycan synthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P39793
A0A6M3ZDQ8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peptidoglycan biosynthetic process
cell wall organization
proteolysis
response to antibiotic
regulation of cell shape

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall organization or biogenesis [inference]

cell wall organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

external encapsulating structure organization [inference]

cell wall organization

response to stimulus [inference]

response to chemical [inference]

response to antibiotic

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of biological quality [inference]

regulation of cell shape

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
serine-type D-Ala-D-Ala carboxypeptidase activity
penicillin binding
peptidoglycan glycosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

peptidoglycan glycosyltransferase activity

hydrolase activity [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity [inference]

serine-type D-Ala-D-Ala carboxypeptidase activity

binding [inference]

amide binding [inference]

penicillin binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

penicillin binding

heterocyclic compound binding [inference]

penicillin binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

penicillin binding

organic cyclic compound binding [inference]

penicillin binding

sulfur compound binding [inference]

penicillin binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K05366

Name

penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]

References

7006606

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements