Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
heparan sulfate 6-O-sulfotransferase 1
Summary
- Gene Symbol
-
- HS6ST1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Coiled coil
- Disease variant
- Glycoprotein
- Hypogonadotropic hypogonadism
- Kallmann syndrome
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O60243 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lung alveolus development | ||
| angiogenesis | ||
| labyrinthine layer blood vessel development | ||
| neuron development | ||
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| Golgi membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| heparan sulfate 6-O-sulfotransferase activity | ||
| sulfotransferase activity |
|
|
| protein binding |
GO Hierarchy
GlycoGene Database (GGDB)
- GGDB ID
- gg031
- Gene Symbol
-
- HS6ST1
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Rattus norvegicus | XP_237060 | XM_237060 |
| Drosophila melanogaster | NP_524409 | NM_079685 |
| Caenorhabditis elegans | NP_508895 | NM_076494 |
| Mus musculus | NP_056633 | NM_015818 |
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11836 | clubfoot | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0060260 | ptosis | |
| DOID:0060261 | congenital ptosis | |
| DOID:0060857 | septooptic dysplasia | |
| DOID:0060870 | isolated growth hormone deficiency | |
| DOID:0060872 | isolated growth hormone deficiency type II | |
| DOID:0060873 | isolated growth hormone deficiency type IA | |
| DOID:0060874 | isolated growth hormone deficiency type IB | |
| DOID:0060875 | isolated growth hormone deficiency type III |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003164 | Hypothalamic gonadotropin-releasing hormone deficiency |
| HP:0003187 | Breast hypoplasia |
| HP:0003782 | Eunuchoid habitus |
| HP:0004349 | Reduced bone mineral density |
| HP:0004409 | Hyposmia |
| HP:0005280 | Depressed nasal bridge |
| HP:0006610 | Wide intermamillary distance |
| HP:0008064 | Ichthyosis |
| HP:0008187 | Absence of secondary sex characteristics |
| HP:0008197 | Absence of pubertal development |
| Disease ID | Disease Name |
|---|---|
| ORPHA:478 |
|
| ORPHA:432 |
|
| OMIM:614880 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 550071 | Xenbase:XB-GENE-953845 | ||
| 113436722 | PSETE08048 | ||
| 100394849 | CALJA37778 | ||
| 105592105 | CERAT34904 | ||
| 715479 | MACMU05511 | ||
| 105492412 | MACNE04941 | ||
| 101126711 | GORGO25950 | ||
| 470530 | PANTR28634 | ||
| 100440521 | PONAB24270 | ||
| 123779490 | URSAM26846 |
