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alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

Mgat2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

94273

KEGG Gene ID

rno:94273

PubChem

94273

Alliance of Genome Resources

RGD:620098

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HBU9	Beta-1,2-N-acetylglucosaminyltransferase II GlcNAc-T II Mannoside acetylglucosaminyltransferase 2 N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II
Q09326	Beta-1,2-N-acetylglucosaminyltransferase II GlcNAc-T II Mannoside acetylglucosaminyltransferase 2 N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
oligosaccharide biosynthetic process	IEA
protein N-linked glycosylation	IBA
protein N-linked glycosylation via asparagine	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasmic side of rough endoplasmic reticulum membrane	ISO
Golgi apparatus	ISO
Golgi membrane	IBA ISO ISS
large ribosomal subunit	ISO
Golgi stack	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

large ribosomal subunit

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of endoplasmic reticulum membrane [inference]

cytoplasmic side of rough endoplasmic reticulum membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein homodimerization activity	ISO ISS
manganese ion binding	ISO ISS
carbohydrate binding	IPI	2952645
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	IBA IDA ISO	2952645

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00736

Name

alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143]

References

2952645

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05985	2.4.1.143	G61751GZ	G39213VZ

Rhea

RHEA:12941

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.143

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070253	congenital disorder of glycosylation type IIa	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	179562	WB:WBGene00001645
Drosophila melanogaster	43563	FB:FBgn0039738
Callorhinchus milii	103175354		CALMI07623
Latimeria chalumnae	102367380		LATCH17986
Danio rerio	100000478	ZFIN:ZDB-GENE-070410-54	DANRE20094
Astyanax mexicanus	103024773		ASTMX15110
Electrophorus electricus	113569808		ELEEL05873
Salmo salar	100195434		SALSA129248
Salmo trutta	115169272		SALTR24436
Salmo trutta	115174519		SALTR53395

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements