GlyCosmos Portal

Submissions

2-ketobutyrate formate-lyase/pyruvate formate-lyase 4

Summary

Gene Symbol

tdcE

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 947623
PubChem: 947623

Annotation

Keyword

Acyltransferase
Cytoplasm
Organic radical
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P42632	Keto-acid formate acetyltransferase Keto-acid formate-lyase Ketobutyrate formate-lyase Pyruvate formate-lyase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
L-threonine catabolic process to propionate	IC IEA	9484901

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

primary metabolic process [inference]

carbohydrate metabolic process

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organic substance metabolic process [inference]

carbohydrate metabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid metabolic process [inference]

aspartate family amino acid metabolic process [inference]

threonine metabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

alpha-amino acid catabolic process [inference]

aspartate family amino acid catabolic process [inference]

threonine catabolic process [inference]

L-threonine catabolic process to propionate

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

L-threonine catabolic process to propionate

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytosol	IBA
cytoplasm	HDA IDA IEA	16858726 9484901
membrane	IDA	16858726

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
2-ketobutyrate formate-lyase activity	IEA IGI	9484901
formate C-acetyltransferase activity	IBA IEA
acyltransferase activity	IEA
protein binding	IPI	28955877

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

acetyltransferase activity [inference]

C-acetyltransferase activity [inference]

formate C-acetyltransferase activity

C-acyltransferase activity [inference]

C-acetyltransferase activity [inference]

formate C-acetyltransferase activity

2-ketobutyrate formate-lyase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements