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scavenger receptor class B member 2

Summary

Gene Symbol

SCARB2

Organism

Homo sapiens (human)

External Links

NCBI Gene

950

PubChem

950

Alliance of Genome Resources

HGNC:1665

JoGo

SCARB2

TogoVar

SCARB2

Annotation

Keyword

3D-structure
Alternative splicing
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Lysosome
Neurodegeneration
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A1W2PRF6
Q14108	85 kDa lysosomal membrane sialoglycoprotein CD36 antigen-like 2 Lysosome membrane protein II Scavenger receptor class B member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
protein targeting to lysosome	NAS	25202012
protein targeting to lysosome	IMP	18022370
protein targeting to lysosome	IBA
receptor-mediated endocytosis	ISS	29199275
receptor-mediated endocytosis	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

aminophospholipid transport

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

organophosphate ester transport [inference]

phospholipid transport [inference]

aminophospholipid transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

aminophospholipid transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of carbohydrate catabolic process

regulation of lipid catabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of membrane lipid metabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process

regulation of lipid metabolic process [inference]

regulation of lipid catabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of membrane lipid metabolic process [inference]

regulation of glucosylceramide catabolic process

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of glucosylceramide catabolic process

regulation of membrane lipid metabolic process [inference]

regulation of glucosylceramide catabolic process

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

regulation of organelle organization [inference]

regulation of vacuole organization [inference]

regulation of lysosome organization

regulation of endosome organization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of glucosylceramidase activity

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS	25202012
cytoplasm
lysosomal membrane	ISS	18022370
lysosomal membrane	TAS	12356916 25202012
lysosomal membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

late endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane

clathrin-coated endocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane

late endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane

clathrin-coated endocytic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
virus receptor activity	IEA
phosphatidylserine binding	ISS	29199275
transmembrane signaling receptor activity	TAS	25202012
scavenger receptor activity	ISS	29199275
scavenger receptor activity	TAS	25202012