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MIRAGE
ADAM metallopeptidase with thrombospondin type 1 motif 2
Summary
- Gene Symbol
-
- ADAMTS2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Collagen degradation
- Disulfide bond
- Ehlers-Danlos syndrome
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| O95450 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| spermatogenesis | ||
| protein processing | ||
| extracellular matrix organization | ||
| collagen fibril organization |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular matrix | ||
| collagen-containing extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity | ||
| zinc ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080733 | Ehlers-Danlos syndrome dermatosparaxis type | |
| DOID:13359 | Ehlers-Danlos syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9509 | Xenbase:XB-GENE-492342 | ||
| 216725 | Xenbase:XB-GENE-492342 | MOUSE04817 | |
| 282401 | BOVIN32058 | ||
| 287899 | RATNO01803 | ||
| 462325 | PANTR37001 | ||
| 481453 | CANLF01981 | ||
| 100029340 | MONDO09178 | ||
| 100224296 | TAEGU04132 | ||
| 100395899 | CALJA26948 | ||
| 100447800 | PONAB29254 |
