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CD44 molecule (IN blood group)

Summary

Gene Symbol

CD44

Aliases

CD44R
CDw44
CSPG8
ECM-III
H-CAM
HCELL
HUTCH-1
HUTCH-I
Hermes-1
IN
In(Lu) related-p80
MC56
PGP-1
Pgp1
chondroitin sulfate proteoglycan 8
extracellular matrix receptor-III
hematopoietic cell E- and L-selectin ligand
homing cell adhesion molecule
phagocyte glycoprotein 1

Organism

Homo sapiens (human)

External Links

NCBI Gene

960

HGNC

1681

KEGG Gene ID

hsa:960

PubChem

960

Alliance of Genome Resources

HGNC:1681

Annotation

Keyword

3D-structure
Alternative splicing
Blood group antigen
Cell adhesion
Cell membrane
Cell projection
Direct protein sequencing
Disulfide bond
Phosphoprotein
Proteoglycan
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P16070	CDw44 Epican Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Heparan sulfate proteoglycan Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
cytokine-mediated signaling pathway	IEA
negative regulation of apoptotic process	IMP	19047049
cell migration	IDA	22726066
hyaluronan catabolic process	IDA	17170110
cellular response to fibroblast growth factor stimulus	IDA	19577615

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

mucopolysaccharide metabolic process [inference]

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell-cell adhesion

leukocyte cell-cell adhesion [inference]

leukocyte aggregation [inference]

monocyte aggregation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell motility [inference]

cell migration

wound healing, spreading of cells

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

cartilage development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to fibroblast growth factor stimulus

response to fibroblast growth factor [inference]

cellular response to fibroblast growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to fibroblast growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of monocyte aggregation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of lamellipodium morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of monocyte aggregation

regulation of heterotypic cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

regulation of leukocyte cell-cell adhesion [inference]

regulation of monocyte aggregation [inference]

positive regulation of monocyte aggregation

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of monocyte aggregation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of monocyte aggregation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of monocyte aggregation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of lamellipodium organization [inference]

regulation of lamellipodium morphogenesis

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [inference]

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
cytosol	IDA
cell surface	IDA	16809613 17170110
plasma membrane	IBA IDA NAS TAS	1991450 20962267
focal adhesion	HDA	21423176
cell projection	IDA	20962267

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

macrophage migration inhibitory factor receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

plasma membrane region [inference]

cell projection membrane [inference]

lamellipodium membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

lamellipodium membrane

cell projection

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IBA
cytokine receptor activity	IBA IDA	17045821
collagen binding		2471973
hyaluronic acid binding	IBA IDA NAS	17170110 17324121 1991450
protein binding	IPI	11207560 20962267 21397861 23855374 29190904

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-containing complex binding [inference]

collagen binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000026508

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K06256

Name

CD44 antigen

References

2466575

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0040085	bacterial sepsis	DisGeNET
DOID:0050387	nonpapillary renal cell carcinoma	DisGeNET
DOID:0050424	familial adenomatous polyposis	DisGeNET DisGeNET DisGeNET DisGeNET
DOID:0050486	exanthem	DisGeNET
DOID:0050523	adult T-cell leukemia/lymphoma	DisGeNET
DOID:0050539	Charcot-Marie-Tooth disease type 2	DisGeNET
DOID:0050572	cone-rod dystrophy	DisGeNET
DOID:0050589	inflammatory bowel disease	DisGeNET DisGeNET DisGeNET
DOID:0050597	intestinal schistosomiasis	DisGeNET
DOID:0050646	distal arthrogryposis	DisGeNET

PubChem Disease

MedGen Diseases

Blood group, Indian system

OMIM Phenotypes

BLOOD GROUP, INDIAN SYSTEM; IN

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	797357	ZFIN:ZDB-GENE-110429-1
Danio rerio	100330801	ZFIN:ZDB-GENE-110429-2
Xenopus laevis	443701	Xenbase:XB-GENE-6251905
Xenopus laevis	108715256	Xenbase:XB-GENE-17344126
Xenopus tropicalis	394545	Xenbase:XB-GENE-487547
Pseudonaja textilis	113440640		PSETE01630
Callithrix jacchus	100390910		CALJA04411
Cercocebus atys	105586800		CERAT16680
Macaca fascicularis	101867504		MACFA09192
Macaca mulatta	717204		MACMU09360

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements