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kallikrein related peptidase 4
Summary
- Gene Symbol
-
- KLK4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amelogenesis imperfecta
- Biomineralization
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5BQA0 |
|
| A0A0C4DFQ5 |
|
| Q9Y5K2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix disassembly | ||
| biomineral tissue development | ||
| protein maturation | ||
| amelogenesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| secretory granule |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| protein binding | ||
| serine-type peptidase activity | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| proteolysis |
| serine-type endopeptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110057 | amelogenesis imperfecta type 2A1 | |
| DOID:10283 | prostate cancer |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9622 | RGD:1303228 | ||
| 56640 | RGD:1303228 | MOUSE51770 | |
| 396720 | PIGXX28345 | ||
| 408210 | RATNO17009 | ||
| 469101 | PANTR19061 | ||
| 484354 | CANLF00750 | ||
| 507800 | BOVIN11610 | ||
| 100067485 | HORSE01412 | ||
| 100067532 | HORSE01411 | ||
| 100344039 | RABIT18410 |
