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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD59 molecule (CD59 blood group)
Summary
- Gene Symbol
-
- CD59
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Glycation
- Hereditary hemolytic anemia
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q6FHM9 |
|
| P13987 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of complement activation | ||
| cell surface receptor signaling pathway | ||
| negative regulation of activation of membrane attack complex | ||
| regulation of complement-dependent cytotoxicity | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| membrane | ||
| endoplasmic reticulum-Golgi intermediate compartment membrane | ||
| focal adhesion | ||
| endoplasmic reticulum membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| complement binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- CD59
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ly-6 antigen/uPA receptor-like |
| Snake toxin-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:1380 | endometrial cancer | |
| DOID:1407 | anterior uveitis | |
| DOID:2394 | ovarian cancer | |
| DOID:2527 | nephrosis | |
| DOID:2921 | glomerulonephritis | |
| DOID:3459 | breast carcinoma | |
| DOID:3498 | pancreatic ductal adenocarcinoma | |
| DOID:5844 | myocardial infarction |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12509 | MGI:109177 | MOUSE34269 | ||
| 25407 | RGD:2311 | RATNO26254 | ||
| 333883 | MGI:1888996 | MOUSE34262 | ||
| 397347 | PIGXX17451 | |||
| 505574 | BOVIN07387 | |||
| 567192 | ZFIN:ZDB-GENE-030131-7871 | |||
| 693402 | MACMU10009 | |||
| 693993 | MACMU10009 | |||
| 739046 | 9598_0:003064 | PANTR02610 | ||
| 100009459 | RABIT01150 |
