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scaffold attachment factor B2

Summary

Gene Symbol

SAFB2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9667

PubChem

9667

Alliance of Genome Resources

HGNC:21605

Annotation

Keyword

Acetylation
Alternative splicing
Cytoplasm
DNA-binding
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repressor
Transcription regulation
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q14151

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of transcription by RNA polymerase II	IBA
regulation of mRNA processing	IBA
Sertoli cell differentiation	IEA
regulation of androgen receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

Sertoli cell differentiation

reproductive process [inference]

developmental process involved in reproduction [inference]

Sertoli cell differentiation

developmental process [inference]

developmental process involved in reproduction [inference]

Sertoli cell differentiation

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

Sertoli cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

regulation of androgen receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

regulation of androgen receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

regulation of androgen receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	IDA
cytoplasm	IEA
nuclear body	IDA
intracellular membrane-bounded organelle	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
RNA binding	HDA	22658674 22681889
protein binding	IPI	12660241 20562859
identical protein binding	IPI	19674106
sequence-specific DNA binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

sequence-specific DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Scaffold attachment factor B2

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
regulation of mRNA processing
sequence-specific DNA binding

Displaying **all 6** entries
InterPro
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily
SAP domain superfamily
SAP domain
Scaffold attachment factor B1/2, RNA binding domain

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6294	Xenbase:XB-GENE-5873119
Xenopus tropicalis	9667	Xenbase:XB-GENE-5873119
Drosophila melanogaster	66660	FB:FBgn0039229
Drosophila melanogaster	79811	FB:FBgn0039229
Mus musculus	224902		MOUSE20248
Rattus norvegicus	301126		RATNO42677
Danio rerio	321979		DANRE23050
Pan troglodytes	455618		PANTR16866
Canis lupus familiaris	476740		CANLF07990
Macaca mulatta	696236		MACMU19485