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calsyntenin 3

Summary

Gene Symbol

CLSTN3

Organism

Homo sapiens (human)

External Links

NCBI Gene

9746

PubChem

9746

Alliance of Genome Resources

HGNC:18371

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell membrane
Cell projection
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Lipid droplet
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BQT9	Alcadein-beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 23 in total

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GO Term	Evidence Code	PMID
regulation of presynapse assembly	IEA
positive regulation of inhibitory synapse assembly
adaptive thermogenesis
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
positive regulation of lipid catabolic process

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

adaptive thermogenesis

cold-induced thermogenesis

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

export from cell [inference]

secretion by cell [inference]

protein secretion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

cold-induced thermogenesis

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

cold-induced thermogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

regulation of localization [inference]

regulation of lipid storage [inference]

negative regulation of lipid storage

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

positive regulation of protein localization to synapse

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

regulation of lipid localization [inference]

negative regulation of lipid localization [inference]

negative regulation of lipid storage

regulation of growth [inference]

regulation of cell growth

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of signaling [inference]

positive regulation of synaptic transmission

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of lipid localization [inference]

negative regulation of lipid storage

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

regulation of cellular component organization [inference]

regulation of cell growth

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

regulation of synapse organization [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

positive regulation of protein localization to synapse

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
cell surface	IBA
GABA-ergic synapse	IEA
organelle membrane contact site
protein-containing complex	IEA
postsynaptic density membrane	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

organelle membrane contact site

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cell-cell adhesion mediator activity	IDA	33101212
amyloid-beta binding
kinesin binding
calcium ion binding	IEA
enzyme inhibitor activity

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

neurexin family protein binding

cytoskeletal protein binding [inference]

kinesin binding

X11-like protein binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **11 - 20** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Oreochromis niloticus	100707828		ORENI08290
Haplochromis burtoni	102303845		HAPBU10856
Astatotilapia calliptera	113031872		ASTCA03969
Sparus aurata	115567293		SPAAU60469
Xenopus laevis	444580	Xenbase:XB-GENE-995427
Xenopus laevis	108696042	Xenbase:XB-GENE-17343668
Xenopus tropicalis	100036725	Xenbase:XB-GENE-5757720
Chrysemys picta bellii	101945906		CHRPI26479
Crocodylus porosus	109319370		CROPO06460
Pseudonaja textilis	113444515		PSETE17197

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Acknowledgements