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Guidelines

MIRAGE

RHO family interacting cell polarization regulator 2

Summary

Gene Symbol

RIPOR2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9750

PubChem

9750

Alliance of Genome Resources

HGNC:13872

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell membrane
Cell projection
Chemotaxis
Coiled coil
Cytoskeleton
Developmental protein
Differentiation
Disease variant
Hearing
Myogenesis
Non-syndromic deafness
Phosphoprotein
Proteomics identification
Reference proteome
Signal transduction inhibitor

Proteins

Displaying **all 8** entries
UniProt	Protein Name
B7Z6U4
F5GX51
B7Z5J9
F5H029
B7Z6D6
Q9Y4F9
A0A2R8YEE0
A0A2R8Y7B3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

1

2

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Last »
GO Term	Evidence Code	PMID
chemotaxis	IEA
cell adhesion	IEA
negative regulation of cell adhesion	ISS
negative regulation of cell adhesion	IMP	23241886
muscle organ development	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemokine

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell differentiation

locomotion [inference]

taxis [inference]

chemotaxis

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemokine

response to chemokine [inference]

cellular response to chemokine

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemokine

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemokine

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemokine

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of T cell migration [inference]

negative regulation of T cell migration

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of neutrophil migration [inference]

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell leading edge

regulation of protein localization to cell leading edge [inference]

negative regulation of protein localization to cell leading edge

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of T cell migration [inference]

negative regulation of T cell migration

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of neutrophil migration [inference]

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell leading edge

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

regulation of myoblast differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

regulation of myoblast fusion [inference]

positive regulation of myoblast fusion

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of cell adhesion [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment of cell polarity

regulation of establishment of T cell polarity [inference]

negative regulation of establishment of T cell polarity

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

regulation of myoblast differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cell differentiation [inference]

positive regulation of myoblast differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell leading edge

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of myoblast fusion

regulation of myoblast fusion [inference]

positive regulation of myoblast fusion

regulation of cell cycle

regulation of cell cycle process [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell leading edge

regulation of protein localization to cell leading edge [inference]

negative regulation of protein localization to cell leading edge

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

regulation of T cell migration [inference]

negative regulation of T cell migration

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of neutrophil migration [inference]

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration [inference]

negative regulation of T cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of granulocyte chemotaxis [inference]

positive regulation of neutrophil chemotaxis

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of Rho guanyl-nucleotide exchange factor activity

positive regulation of molecular function [inference]

positive regulation of binding [inference]

negative regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of Rho guanyl-nucleotide exchange factor activity

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of Rho guanyl-nucleotide exchange factor activity

regulation of binding [inference]

positive regulation of binding [inference]

negative regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of Rho guanyl-nucleotide exchange factor activity

regulation of GTP binding [inference]

regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of guanyl-nucleotide exchange factor activity [inference]

negative regulation of Rho guanyl-nucleotide exchange factor activity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cytoplasm	IDA	17150207 23241886 24687993
cytosol	IDA
cytoskeleton	IDA	17150207
apical plasma membrane	IEA
filopodium	IDA	17150207

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

neuron projection membrane [inference]

stereocilium membrane

leading edge membrane [inference]

neuron projection membrane [inference]

stereocilium membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

stereocilium

actin-based cell projection [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21988832 23241886 24687993 25416956 27556504 28169274 32296183
14-3-3 protein binding	IDA	24687993 27556504

GO Hierarchy

molecular function

binding [inference]

protein binding

14-3-3 protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rho family-interacting cell polarization regulator 2

Functional Category

G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cell differentiation
chemotaxis
muscle organ development
sensory perception of sound

Displaying **all 4** entries
InterPro
Armadillo-like helical
Armadillo-type fold
FAM65, N-terminal
RIPOR family member 3

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110465	autosomal recessive nonsyndromic deafness 104	Alliance of Genome Resources
DOID:0110551	autosomal dominant nonsyndromic deafness 21	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	9750	Xenbase:XB-GENE-5965443
Caenorhabditis elegans	75687	WB:WBGene00045063
Caenorhabditis elegans	79567	WB:WBGene00045063
Caenorhabditis elegans	140876	WB:WBGene00045063
Mus musculus	193385		MOUSE10647
Rattus norvegicus	306934		RATNO12425
Pan troglodytes	462479		PANTR37361
Canis lupus familiaris	488247		CANLF13784
Bos taurus	539635		BOVIN19085
Danio rerio	563800		DANRE14917

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Last updated: December 8, 2025