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MIRAGE
piezo type mechanosensitive ion channel component 1 (Er blood group)
Summary
- Gene Symbol
-
- PIEZO1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Blood group antigen
- Cell membrane
- Cell projection
- Coiled coil
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Hereditary hemolytic anemia
- Ion channel
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q92508 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation transport | ||
| positive regulation of myotube differentiation | ||
| positive regulation of integrin activation | ||
| positive regulation of cell-cell adhesion mediated by integrin | ||
| regulation of membrane potential |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation channel activity | ||
| monoatomic cation channel activity | ||
| protein binding | ||
| mechanosensitive monoatomic ion channel activity | ||
| mechanosensitive monoatomic cation channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Piezo-type mechanosensitive ion channel component
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Piezo family |
| Piezo non-specific cation channel, R-Ras-binding domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050580 | hereditary lymphedema | |
| DOID:0111576 | dehydrated hereditary stomatocytosis 1 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9780 | Xenbase:XB-GENE-987183 | ||
| 63895 | FB:FBgn0267430 | ||
| 182492 | Xenbase:XB-GENE-6050252 | ||
| 234839 | Xenbase:XB-GENE-6050252 | MOUSE59063 | |
| 361430 | Xenbase:XB-GENE-987183 | RATNO15157 | |
| 454306 | PANTR13067 | ||
| 489662 | CANLF15860 | ||
| 567949 | DANRE41917 | ||
| 667742 | FB:FBgn0264953 | ||
| 711216 | MACMU26952 |
