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C2 calcium dependent domain containing 5

Summary

Gene Symbol

C2CD5

Organism

Homo sapiens (human)

External Links

NCBI Gene

9847

PubChem

9847

Alliance of Genome Resources

HGNC:29062

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Lipid-binding
Metal-binding
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B7ZLK1
Q86YS7	C2 domain-containing phosphoprotein of 138 kDa

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of protein targeting to membrane	IBA IMP	21907143
positive regulation of vesicle fusion	IBA IMP	21907143
intracellular protein transmembrane transport	IBA IMP	21907143
insulin receptor signaling pathway	IDA ISS	21907143
positive regulation of glucose transmembrane transport	IBA ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transport [inference]

positive regulation of vesicle fusion

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

regulation of vesicle-mediated transport [inference]

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of transport [inference]

positive regulation of vesicle fusion

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of vesicle-mediated transport [inference]

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
centriolar satellite	IDA
cell cortex	IDA	21907143
cytoplasmic vesicle membrane	IDA	21907143
ruffle membrane	IDA	21907143
plasma membrane	IBA IDA	21907143

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

leading edge membrane [inference]

ruffle membrane

centriolar satellite

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
calcium-dependent phospholipid binding	IBA IDA	21907143
calcium ion binding	IBA IDA	21907143

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

calcium-dependent phospholipid binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

c2 domain-containing protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
calcium-dependent phospholipid binding

Displaying **all 2** entries
InterPro
C2 domain superfamily
C2 domain

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	42904		FB:FBgn0039187
Mus musculus	74741		MGI:1921991	MOUSE48105
Rattus norvegicus	362461		RGD:1304592	RATNO31501
Danio rerio	393585		ZFIN:ZDB-GENE-041114-193	DANRE14693
Xenopus laevis	398515		Xenbase:XB-GENE-5915042
Pan troglodytes	465342	9598_0:003604		PANTR06301
Xenopus tropicalis	733979		Xenbase:XB-GENE-5915013
Equus caballus	100068403			HORSE35943
Pongo abelii	100171977	9601_0:00348f		PONAB04969
Taeniopygia guttata	100225972			TAEGU09075