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Guidelines

MIRAGE

septin 7

Summary

Gene Symbol

SEPTIN7

Organism

Homo sapiens (human)

External Links

NCBI Gene

989

PubChem

989

Alliance of Genome Resources

HGNC:1717

JoGo

SEPTIN7

TogoVar

SEPTIN7

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Centromere
Chromosome
Coiled coil
Cytoskeleton
Flagellum
GTP-binding
Kinetochore
Mitosis
Phosphoprotein
Proteomics identification
Reference proteome
Spermatogenesis

Proteins

Displaying **all 6** entries
UniProt	Protein Name
A0A024RA87
G3V1Q4
Q16181	CDC10 protein homolog
A0A023T695
A8K3D0
B4DNE4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
spermatogenesis	IEA
protein localization	IBA
regulation of embryonic cell shape	ISS
cell differentiation	IEA
cilium assembly	ISS

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis

cellular developmental process [inference]

cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular developmental process [inference]

cell differentiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape [inference]

regulation of embryonic cell shape

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

regulation of embryonic cell shape

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of non-motile cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of non-motile cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of non-motile cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of non-motile cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of non-motile cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly [inference]

positive regulation of non-motile cilium assembly

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

regulation of embryonic cell shape

regulation of biological quality [inference]

regulation of cell shape [inference]

regulation of embryonic cell shape

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
kinetochore	IEA
stress fiber	IDA	15485874
nucleus	IDA	15485874
spindle	IEA
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

septin complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

non-motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

non-motile cilium

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

septin cytoskeleton [inference]

septin ring

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

septin cytoskeleton [inference]

septin ring

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

sperm annulus

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
GTPase activity	IBA
structural molecule activity	TAS	8037772
protein binding	IPI	11584266 15485874 17637674 17685441 18330356 19145258 24633326 25416956 25588830 30021884 31515488 32814053 33961781 35271311
GTP binding	IEA
identical protein binding	IPI	22064074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

structural molecule activity

binding [inference]

protein binding

identical protein binding

cell adhesion molecule binding [inference]

cadherin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Septin

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
GTP binding
cytoskeleton-dependent cytokinesis
nucleotide binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Septin-type guanine nucleotide-binding (G) domain
Septin

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: April 6, 2026