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synaptosome associated protein 91

Summary

Gene Symbol

SNAP91

Organism

Homo sapiens (human)

External Links

NCBI Gene

9892

PubChem

9892

Alliance of Genome Resources

HGNC:14986

Annotation

Keyword

Alternative splicing
Cell membrane
Coated pit
Glycoprotein
Methylation
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O60641	91 kDa synaptosomal-associated protein Clathrin coat-associated protein AP180 Phosphoprotein F1-20
B7Z2N2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein transport	IEA
synaptic vesicle budding from presynaptic endocytic zone membrane	IBA
clathrin-dependent endocytosis	IBA
regulation of clathrin-dependent endocytosis	IMP	16254249
clathrin coat assembly	IEA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane [inference]

synaptic vesicle budding [inference]

synaptic vesicle budding from presynaptic endocytic zone membrane

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

membrane organization [inference]

vesicle budding from membrane [inference]

synaptic vesicle budding [inference]

synaptic vesicle budding from presynaptic endocytic zone membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
clathrin-coated vesicle	IBA
extrinsic component of presynaptic endocytic zone membrane	IBA
synaptic vesicle	IBA
clathrin-coated pit	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

clathrin-coated pit

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of presynaptic membrane [inference]

extrinsic component of presynaptic endocytic zone membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	17762867 32296183 32814053
SNARE binding	IBA
phosphatidylinositol-4,5-bisphosphate binding	IBA
clathrin heavy chain binding	IBA
protein kinase binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

SNARE binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

clathrin binding [inference]

clathrin heavy chain binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

1-phosphatidylinositol binding

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

clathrin assembly

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
1-phosphatidylinositol binding
SNARE binding
clathrin binding
clathrin coat assembly
clathrin heavy chain binding
clathrin-dependent endocytosis
phosphatidylinositol-4,5-bisphosphate binding
phospholipid binding

Displaying **all 5** entries
InterPro
ANTH domain superfamily
AP180 N-terminal homology (ANTH) domain
Clathrin coat assembly protein AP180-like
ENTH domain
ENTH/VHS

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:3525	middle cerebral artery infarction	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 80 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Pan troglodytes	740887	9598_0:001baa		PANTR38626
Saccharomyces cerevisiae S288C	853157		SGD:S000003473
Saccharomyces cerevisiae S288C	856566		SGD:S000001204
Equus caballus	100065464			HORSE00743
Ornithorhynchus anatinus	100076061			ORNAN10673
Xenopus tropicalis	100170497		Xenbase:XB-GENE-1013213
Pongo abelii	100173636			PONAB32145
Pongo abelii	100189926	9601_0:001a24		PONAB32145
Taeniopygia guttata	100222112			TAEGU21289
Oryctolagus cuniculus	100355946			RABIT02623

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements