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non-SMC condensin I complex subunit D2

Summary

Gene Symbol

NCAPD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9918

PubChem

9918

Alliance of Genome Resources

HGNC:24305

Annotation

Keyword

Chromosome
Cytoplasm
DNA condensation
Direct protein sequencing
Disease variant
Mitosis
Nucleus
Phosphoprotein
Primary microcephaly
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q15021	Chromosome condensation-related SMC-associated protein 1 Chromosome-associated protein D2 Non-SMC condensin I complex subunit D2 XCAP-D2 homolog
B3KY03
B3KMS0

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
mitotic chromosome condensation	NAS	10958694
mitotic chromosome condensation	IDA	11136719
mitotic chromosome condensation	IMP	27737959
mitotic chromosome condensation	IBA
meiotic chromosome condensation	IBA

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

mitotic cell cycle process [inference]

mitotic chromosome condensation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome condensation [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

reproductive process [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

meiotic chromosome condensation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of chromosome organization [inference]

regulation of chromosome condensation [inference]

positive regulation of chromosome condensation

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of chromosome condensation

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of chromosome segregation [inference]

positive regulation of chromosome segregation

regulation of chromosome separation [inference]

positive regulation of chromosome separation

positive regulation of cell cycle process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

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GO Term	Evidence Code	PMID
nuclear chromosome	IDA	12138188
condensed chromosome, centromeric region	IBA
condensed chromosome	IDA	12138188
condensed nuclear chromosome	ISO
condensin complex	NAS	10958694 17268547

GO Hierarchy

cellular component

protein-containing complex [inference]

condensin complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

ciliary basal body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome

condensed nuclear chromosome

condensed chromosome

condensed nuclear chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome

condensed nuclear chromosome

condensed chromosome

condensed nuclear chromosome

chromosomal region [inference]

chromosome, centromeric region [inference]

condensed chromosome, centromeric region

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12138188 17268547 24981860 26496610 35271311
histone binding	NAS	10958694
histone binding	IDA	12138188
histone binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

histone binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CONDENSIN

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism

Displaying **all 5** entries
Gene Ontology
cell cycle
cell division
histone binding
meiotic chromosome condensation
mitotic chromosome condensation

Displaying **all 6** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Condensin complex subunit 1, C-terminal
Condensin complex subunit 1, N-terminal
Condensin subunit 1/Condensin-2 complex subunit D3
Condensin subunit 1

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070296	primary autosomal recessive microcephaly	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	9918	Xenbase:XB-GENE-5854776
Mus musculus	68298		MOUSE48656
Rattus norvegicus	362438		RATNO31451
Canis lupus familiaris	477715		CANLF11151
Macaca mulatta	712834		MACMU02914
Pan troglodytes	747674		PANTR04941
Bos taurus	786159		BOVIN30470
Monodelphis domestica	100015092		MONDO34013
Equus caballus	100059757		HORSE37492
Taeniopygia guttata	100230670		TAEGU10263

GlyTouCan

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements