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cell division cycle 25B

Summary

Gene Symbol

CDC25B

Organism

Homo sapiens (human)

External Links

NCBI Gene

994

PubChem

994

Alliance of Genome Resources

HGNC:1726

Annotation

Keyword

3D-structure
Alternative splicing
Cytoskeleton
Mitosis
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome

Proteins

Displaying **all 8** entries
UniProt	Protein Name
G8JLH2
Q6MZW8
P30305	Dual specificity phosphatase Cdc25B
B4DQZ3
E1YMX4
B4DRC3
B3KS38
B4DIG0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
G2/M transition of mitotic cell cycle	TAS	12400006
G2/M transition of mitotic cell cycle	IBA
mitotic cell cycle	TAS	9188863
oocyte maturation	IEA
chromatin remodeling	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

macromolecule modification [inference]

protein modification process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G2/M transition of mitotic cell cycle

cell cycle G2/M phase transition [inference]

G2/M transition of mitotic cell cycle

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiosis I [inference]

female meiosis I

meiotic nuclear division [inference]

meiosis I [inference]

female meiosis I

female meiotic nuclear division [inference]

female meiosis I

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G2/M transition of mitotic cell cycle

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

female meiotic nuclear division [inference]

female meiosis I

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

dephosphorylation [inference]

protein dephosphorylation

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

meiosis I [inference]

female meiosis I

female meiotic nuclear division [inference]

female meiosis I

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

reproductive process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

female meiotic nuclear division [inference]

female meiosis I

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiosis I [inference]

female meiosis I

meiotic nuclear division [inference]

meiosis I [inference]

female meiosis I

female meiotic nuclear division [inference]

female meiosis I

developmental process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

oocyte maturation

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of cell division [inference]

positive regulation of cytokinesis

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
spindle pole	IDA	15908796
nucleus	IBA
nucleoplasm	TAS
cytoplasm	IBA
centrosome	IDA	15908796

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10713667 12766774 15629715 16672277 26496610 28514442 32296183 33961781 35271311 36931259 7644510
protein kinase binding	IPI	12400006 15908796
protein tyrosine phosphatase activity, metal-dependent	IEA
histone H2AXY142 phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

M-phase inducer phosphatase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
G2/M transition of mitotic cell cycle
cell cycle
cell division
hydrolase activity
phosphoprotein phosphatase activity
positive regulation of G2/MI transition of meiotic cell cycle
positive regulation of cell cycle G2/M phase transition
protein dephosphorylation
protein tyrosine phosphatase activity

Displaying **all 3** entries
InterPro
M-phase inducer phosphatase
Rhodanese-like domain superfamily
Rhodanese-like domain

Ortholog

Displaying entries **31 - 40** of 49 in total

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Species	Gene ID	Orthologous MAtrix
Carlito syrichta	103268973	CARSF12471
Nannospalax galili	103743120	NANGA26195
Rhinopithecus roxellana	104674594	RHIRO05421
Pteropus vampyrus	105298511	PTEVA06659
Macaca nemestrina	105481578	MACNE22633
Mandrillus leucophaeus	105535831	MANLE13272
Cercocebus atys	105582133	CERAT03182
Aotus nancymaae	105719330	AOTNA04933
Propithecus coquereli	105806205	PROCO15979
Dipodomys ordii	105981746	DIPOR03534

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

International Collaboration

Acknowledgements